[1]李超,杨利霞#,甄艳华.子宫内膜癌经阴道彩色多普勒超声征象与微血管密度相关性分析[J].郑州大学学报(医学版),2009,(02):422-424.
 LI Chao,YANG Lixia,ZHEN Yanhua.Correlation between transvaginal color doppler sonography features and MVD in endometrial cancer[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2009,(02):422-424.
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子宫内膜癌经阴道彩色多普勒超声征象与微血管密度相关性分析()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2009年02期
页码:
422-424
栏目:
论著
出版日期:
2009-03-01

文章信息/Info

Title:
Correlation between transvaginal color doppler sonography features and MVD in endometrial cancer
作者:
李超杨利霞#甄艳华
郑州大学第二附属医院超声科郑州450014
Author(s):
LI ChaoYANG LixiaZHEN Yanhua
Department of Ultrasound,the Second Affiliated Hospital,Zhengzhou University,Zhengzhou 450014
关键词:
子宫内膜癌经阴道彩色多普勒超声微血管密度
Keywords:
endometrial cancertransvaginal color doppler sonographymicrovessel density
分类号:
R737.33
摘要:
探讨子宫内膜癌经阴道彩色多普勒超声(TVCDS)征象与癌组织中微血管密度(MVD)的关系。方法:32例经手术病理证实的子宫内膜癌患者术前经阴道彩色多普勒超声记录内膜厚度、形态、回声特点、肌壁浸润深度、宫旁浸润及淋巴结转移、血流分级、阻力指数(RI),术后采用免疫组织化学SP法检测癌组织中的MVD,与TVCDS征象进行对照分析。结果:子宫内膜癌组织中MVD为(27.03±15.03),TVCDS征象中内膜厚度、肌壁浸润深度、宫旁浸润及淋巴结转移、血流级别与MVD均有相关性(P<0.05),肿瘤的形态和回声特点与MVD无关(P>0.05);RI与MVD成负相关(r=-0.743,P<0.05),与内膜厚度、肌壁浸润深度及血流分级均有关(P<0.05)。结论:TVCDS征象可间接反映肿瘤新生血管生成程度,可为预测子宫内膜癌的发展、转移及预后,为临床肿瘤分期及制定治疗方案提供客观依据。
Abstract:
To study the correlation between the features of transvaginal color doppler sonography (TVCDS) and microvessel density(MVD) in endometrial cancer(EC).Methods:Thirtytwo cases of EC proved by the surgery and pathology and examined with TVCDS scanning were analyzed retrospectively. Endometrial thickness, morphology, echo,depth of myometrial invasion, blood flow grade, the metastasis near the tumor, lymph node metastasis and the resistance index (RI) were recorded. MVD was detected with immunohistochemical SP method.Results:The MVD was (27.03±15.03) in EC. There were correlations between the endometrial thickness,depth of myometrial invasion, blood flow grade, RI and MVD(P<0.05);however,there were no correlation between morphology, echo and MVD(P>0.05). There was a negative linear correlation between MVD and RI(r=-0.743,P<0.05).There were correlations between the endometrial thickness, depth of myometrial invasion, blood flow grade and RI (P<0.05).Conclusion: The TVCDS features of EC can reflect angiogenesis,predict the biologic behavior characters and provide information for clinical stage and the therapeutic procedure.

参考文献/References:

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备注/Memo

备注/Memo:
#通讯作者,女,1952年生,教授,主任医师,研究方向:腹部疾病的超声诊断,Email:ylixia@263.net
更新日期/Last Update: 2010-05-17