[1]王瑞)#,张天标),张卫星),等.无精症患者睾丸病理、性激素水平及睾丸容积检测*[J].郑州大学学报(医学版),2009,(03):483-485.
 WANG Rui),ZHANG Tianbiao),ZHANG Weixing),et al.Testicular biopsy and determination of sexual hormone and testicular volume in patients with azoospermia[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2009,(03):483-485.
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无精症患者睾丸病理、性激素水平及睾丸容积检测* ()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2009年03期
页码:
483-485
栏目:
应用研究
出版日期:
2009-05-01

文章信息/Info

Title:
Testicular biopsy and determination of sexual hormone and testicular volume in patients with azoospermia
作者:
王瑞1)#张天标1)张卫星1)李松1)韩广业1)李征1)陈朋飞2)
1)郑州大学第一附属医院泌尿外科;河南省高等学校临床医学重点学科开放实验室;郑州大学肿瘤分子外科研究所郑州4500522)河南中医学院第二附属医院男科郑州450003
Author(s):
WANG Rui1)ZHANG Tianbiao1)ZHANG Weixing1)LI Song1)HAN Guangye1)etc
关键词:
无精症睾丸活检病理性激素睾丸容积
Keywords:
azoospermiatesticular biopsypathology reproductive hormonetesticular volume
分类号:
R698+.2
摘要:
观察无精症患者睾丸病理、血清性激素水平及睾丸容积变化。方法:对97例无精症患者[A组32例(唯支持细胞综合征),B组28例(精子发育停滞于精母细胞)、C组37例(生精功能低下)]与正常对照40例(D组)进行睾丸活检病理、性激素和睾丸容积检测。结果:A、B、C组FSH和Johnsen评分均有差异(P<0.05)。A、B组睾丸容积低于C、D组,而LH水平高于C、D组 (P<0.05),B组E2水平低于其他各组(P<0.05)。结论:FSH结合睾丸活检病理与睾丸容积可作为判断睾丸生精功能的重要指标。
Abstract:
To observe the testicular pathology and changes in serum levels of the reproductive hormones and testicular volume in patients with azoospermia.Methods:A total of 97 patients with azoospermia were allocated into group A:32 cases of sertoli cell only symdrome, groups B: 28 cases of germinal arrest in the spermatocyte, groups C: 37 cases of hypospermatogenesis.Testicular biopsy, the reproductive hormones and the testicular volume were examined, and 40 normal individuals were chosen as control group.Results:FSH and Johnsen score of group A, B and C had significant differences (P<0.05).

参考文献/References:

[1]Zopfgen A,Priem F,Sudhoff F,et al. Relationship between semen quality and the seminal plasma components carnitine,alphaglucosidase,fructose,citrate and granulocyte elastase in infertile men compared with a normal population[J]. Hum Reprod,2004,15(4):840
[2]郭应禄,胡礼泉.男科学[M].北京:人民卫生出版社,2004:992
[3]张卫星,王瑞,李培强.血清和精浆抑制素B在无精子症诊断中的应用研究[J].中华男科杂志,2007,13(7):598
[4]Christiansen P, Andersson AM, Skakkebaek NE,et al. Serum inhibin B, FSH, LH and testosterone levels before and after human chorionic gonadotropin stimulation in prepubertal boys with cryptorchidism[J]. Eur J Endocrinol,2002,147(1):95
[5]Andersson AM, Muller J, Skakkebaek NE. Different roles of prepubertal and postpubertal germ cells and Sertoli cells in the regulation of serum inhibin B levels [J] .Clin Endocrinol Metab,1998,83(12):4 451

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[1]王瑞)#,张卫星),张天标),等.益肾生精冲剂治疗睾丸性无精症7例*[J].郑州大学学报(医学版),2009,(03):504.
[2]欧蕾),郭艺红)#,孙莹璞),等.睾丸、附睾精子冻融后行卵胞浆内单精子注射疗效观察[J].郑州大学学报(医学版),2011,(01):134.
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备注/Memo

备注/Memo:
*河南省医学科技攻关基金资助项目20060037;河南省自然科学基金资助项目72102310025;河南省医学科技攻关基金资助项目200703014#通讯作者,男,1963年生,硕士,教授,研究方向:男科学,Email:huzi918@hotmail.com
更新日期/Last Update: 2010-05-28