[1]张艳敏)),孙国清),张郑民),等.河南省艾滋病流行区HIV共感染HBV和HCV状况分析*[J].郑州大学学报(医学版),2009,(03):542-544.
 ZHANG Yanmin)),SUN Guoqing),ZHANG Zhengmin),et al.Relative analysis on HIV coinfected HBV and HCV in the area of epidemic disease, Henan[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2009,(03):542-544.
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河南省艾滋病流行区HIV共感染HBV和HCV状况分析*()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2009年03期
页码:
542-544
栏目:
论著
出版日期:
2009-05-01

文章信息/Info

Title:
Relative analysis on HIV coinfected HBV and HCV in the area of epidemic disease, Henan
作者:
张艳敏1)2)孙国清3)张郑民1)高葆真3)鲍玉洲12)#
1)河南省眼科研究所分子生物室郑州4500032)郑州大学基础医学院生物化学与分子生物学教研室郑州4500013)河南省CDC性病、HIV研究所郑州450016
Author(s):
ZHANG Yanmin1)2)SUN Guoqing3)ZHANG Zhengmin1)GAO Baozhen3)etc
关键词:
艾滋病病毒载量聚合酶链式反应乙型肝炎病毒丙型肝炎病毒
Keywords:
HIV virus loadingPCRHBVHCV
分类号:
R512.91
摘要:
了解河南省艾滋病流行区艾滋病病毒(HIV)共感染乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)状况。方法:首先用 Combas Amplicor HIV1病毒载量检测法对从我省HIV某高发县采集的由输血感染HIV1的130份血样进行定量测定。挑选出HIV1病毒载量4.28×102拷贝/mL以上的血浆样本81份,同时收集30份HIV1阴性健康体检者血浆作为对照,再用巢式PCR法对以上样本进行HBV和HCV测定。结果:81份HIV1阳性样本中HBV阳性32份(39.5%),HCV阳性72份(88.9%);同时感染HBV和HCV的样本为7份(8.6%)。30份HIV1阴性对照组中,HBV阳性7份(23.3%),与HIV1阳性组间比较差异无统计学意义(χ2=2.51,P>0.05);HCV阳性4份(13.3%),与HIV1阳性组间比较差异有统计学意义(χ2=57.88,P<0.05);
Abstract:
To investigate the relativity between HIV coinfected by HBV and HCV by blood transfusion.Methods:130 blood samples of HIV1 infected by blood transfusion were collected by a high epidemic county, Henan. 81 samples which HIV1 virus numbers over 4.28×102 copies/mL were selected and 30 blood samples of health human were collected. HBV and HCV were determined by the above samples and by nested PCR.

参考文献/References:

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备注/Memo

备注/Memo:
*河南省科技攻关基金资助项目0624410059#通讯作者,男,1955年生,硕士,研究员,研究方向:重大致病微生物检测方法学,Email:baoyuzhou@126.com
更新日期/Last Update: 2010-05-28