[1]单娟,袁翎#,卜珊珊.肺癌化学治疗联合适形放疗中放射性肺炎的影响因素[J].郑州大学学报(医学版),2009,(03):619-621.
 SHAN Juan,YUAN Ling,BU Shanshan.Influencing factors of occurrence of radiation pneumonitis after combined therapy of chemotherapy and 3DCRT for lung cancer[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2009,(03):619-621.
点击复制

肺癌化学治疗联合适形放疗中放射性肺炎的影响因素()
分享到:

《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2009年03期
页码:
619-621
栏目:
论著
出版日期:
2009-05-01

文章信息/Info

Title:
Influencing factors of occurrence of radiation pneumonitis after combined therapy of chemotherapy and 3DCRT for lung cancer
作者:
单娟袁翎#卜珊珊
河南省肿瘤医院放疗科郑州450003
Author(s):
SHAN Juan YUAN LingBU Shanshan
Department of Radiation, Henan Provincial Tumor Hospital, Zhengzhou 450003
关键词:
放射性肺炎三维适形放疗化疗
Keywords:
radiation pneumonia 3dimension conformal radiotherapy chemotherapy
分类号:
R734.2
摘要:
分析化疗联合适形放疗治疗肺癌中出现放射性肺炎的影响因素。方法:选择81例肺癌患者进行回顾性分析,全部患者均接受了三维适形放疗加化疗。观察性别、年龄、KPS评分、体质量有无减轻、吸烟史、病理分类、病理分期、放疗靶体积、肿瘤剂量、V20、肺平均剂量、照射肿瘤位置、放化疗方案、紫杉醇有无等14个因素对放化疗中出现放射性肺炎的影响。结果:81例中32例出现放射性肺炎,发生率为39.5%(32/81)。发生时间多在放疗后1~4个月。年龄、KPS评分、病理分类及分期、放疗靶体积、肿瘤剂量与放射性肺炎的发生有关。结论:化疗联合适形放疗中放射性肺炎的发生和年龄、KPS评分、病理分类与分期、放疗靶体积及肿瘤剂量有关。
Abstract:
To analyze the influencing factors of radiation pneumonia in lung cancer treatments with chemotherapy and 3DCRT.Methods:Review the 81 patients with lung cancer who had accepted treatments of chemotherapy and 3DCRT.The influence of the following factors(sex,age, KPS,weight loss,history of smoking,pathological types,pathological staging, target volume,tumor dose,V20,average dose of lung,tumor site,programes of radiotherapy and chemotherapy,with or without paclitaxel) were evaluated on the occurrence of radiation pneumonia.

参考文献/References:

[1]殷蔚伯,谷铣之.肿瘤放射治疗学[M].3版.北京:中国协和医科大学出版社,2002:675
[2]Robnett TJ,Machtay M,Vines EF,et al.Factors predicting severe radiation pneumonitis in patients receiving definitive chemoradiation for lung cancer[J]. Int J Radiat Oncol Biol Phys,2000,48(1):89
[3]Steel GG.Gossary of the terms in radiation biology in:Steel GG,eds Basic Clinical Radiobiology[M].2nd ed.London:Arnold,1997:249
[4]Graham MV, Purdy JA, Emami B, et al. Clinical dosevolume histogram analysis for pneumonitis after 3D treatment for nonsmall cell lung cancer (NSCLC)[J].Int J Radiat Oncol Biol Phys,1999,45(2):323

相似文献/References:

[1]郑瑞锋),尹继云),杨波),等. 脑恶性胶质瘤调强放疗和三维适形放疗剂量比较[J].郑州大学学报(医学版),2011,(02):303.
 [J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2011,(03):303.
[2]王跃伟),刘建波)#,李会荣),等.脑恶性胶质瘤术后适形放疗联合不同形式化疗的临床观察[J].郑州大学学报(医学版),2012,(03):370.
 WANG Yuewei),LIU Jianbo),LI Huirong),et al.Effects of threedimensional conformal radiotherapy combined with different chemotherapy in treatment of postoperative malignant glioma[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2012,(03):370.

备注/Memo

备注/Memo:
#通讯作者,男,1965年生,博士,主任医师,研究方向:肿瘤的综合治疗,Email:ZGHNZZYL2006@yahoo.com.cn
更新日期/Last Update: 2010-05-28