[1]朱庆华)△,王桂芳),张小俊),等.不同程度冠状动脉病变患者血清胆红素、尿酸水平检测[J].郑州大学学报(医学版),2009,(03):646-647.
 ZHU Qinghua),WANG Guifang),ZHANG Xiaojun),et al.Determination of serum billirubin and uric acid level in patients with different lesion degree coronary heart disease[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2009,(03):646-647.
点击复制

不同程度冠状动脉病变患者血清胆红素、尿酸水平检测()
分享到:

《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2009年03期
页码:
646-647
栏目:
论著
出版日期:
2009-05-01

文章信息/Info

Title:
Determination of serum billirubin and uric acid level in patients with different lesion degree coronary heart disease
作者:
朱庆华1)王桂芳2)张小俊2)韩战营3)
1)郑州大学第一附属医院检验科郑州4500522)郑州大学医学科学研究院郑州4500523)郑州大学第一附属医院心血管内科郑州450052
Author(s):
ZHU Qinghua1)WANG Guifang2)ZHANG Xiaojun2)HAN Zhanying3)
关键词:
胆红素尿酸冠心病冠状动脉造影
Keywords:
bilirubinuric acidcoronary heart diseasecoronary angiography
分类号:
R541.4
摘要:
分析血清胆红素(Bil)和尿酸(UA)水平与冠心病(CHD)病变程度的关系。方法:选择200例经临床确诊为冠心病的患者为病变组,按冠状动脉病变程度分为A组(单支病变组)、B组(多支病变组),115例体检证实健康者为对照组。采用全自动生化分析仪检测各组患者血清总胆红素(TBil)、直接胆红素(DBil)、间接胆红素(IBil)与UA水平。结果:A、B组血清TBil、DBil、IBil水平均低于对照组,且B组以上各指标均低于A组;A、B组血清UA水平均高于对照组,且B组高于A组(P均<0.05)。结论:血清Bil和UA水平可反映冠状动脉病变程度,联合检测2者可间接评估其严重程度。
Abstract:
To determine the serum billirubin and uric acid(UA) level in patients with different lesion degree coronary heart disease.Methods:A total of 200 patients with CHD diagnosis were allocated into group A (one vessel lesion) and group B(multifold vessel lesion) according to CHD grade, and 115 healthy individuals as normal controls.The serum TBil,DBil,IBil and UA were determined with automatic biochemical analyzer.

参考文献/References:

[1]Schwertner HA, Jackson WG, Tolan G. Association of low serum concentration of bilirubin with increased risk of coronary artery disease[J]. Clin Chem,1994,40(1):18
[2]Culletion BF,Larson MG,Kannel WB,et al.Serum uric acid and risk for cardiovascular disease and dease:the Framingham heart study [J] .Ann Intern Med,1999,131(1):7
[3]陈灏珠. 心脏病学[M]. 北京:人民卫生出版社,2005:226
[4]薛邦录,刘彤,刘毅,等. 血清胆红素浓度与冠心病的关系探讨[J].国外医学:临床生物化学与检验学分册,2005,26(11):778
[5]Sharma HS, Das DK, Verdouw PD. Enhanced expression and localization of heme oxygenase1 during recovery phase of porcine stunned myocardium[J]. Mol Cell Biochem, 1999,196 (1/2):133
[6]杜菊兰, 万汝根. 胆红素含量与冠心病的关系[J].中华检验医学杂志,2003,26(10):624
[7]党爱民,刘国仗. 尿酸与心血管事件[J].中华心血管杂志,2003,31(6):478
[8]党爱民,刘国仗,张宇辉,等.血管紧张素Ⅱ受体拮抗剂干预高血压患者尿酸代谢的对比研究[J].中华心血管病杂志,2006,34(10):882

相似文献/References:

[1]刘金玲,滕军放.脑梗死患者颈动脉粥样硬化斑块稳定性与血C反应蛋白、尿酸水平的关系[J].郑州大学学报(医学版),2010,(04):609.
 [J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2010,(03):609.
[2]刘桂芝.高尿酸血症患者心电图J波发生情况调查[J].郑州大学学报(医学版),2011,(04):647.
[3]王彦芳),阚全程)#,余祖江),等.高血氨对大鼠血清胆红素及肝组织血红素加氧酶1、尿苷二磷酸葡萄糖醛酸转移酶1A1表达的影响[J].郑州大学学报(医学版),2013,(04):489.
 WANG Yanfang),KAN Quancheng),YU Zujiang),et al.Effects of hyperammonemia on rat serum bilirubin and expressions of heme oxygenase1 and UDPglucuronosyltransferase 1A1 in liver tissue[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2013,(03):489.
[4]王楠,何远宏,潘双杰.阿尔茨海默病患者认知功能及血清铜、同型半胱氨酸、尿酸水平、tau和Aβ142蛋白的检测*[J].郑州大学学报(医学版),2015,(03):407.
 WANG Nan,HE Yuanhong,PAN Shuangjie.Detection of serum copper,Hcy,uric acid,tau and Aβ142 protein levels and cognitive function of patients with Alzheimer disease[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2015,(03):407.

备注/Memo

备注/Memo:
△男,1966年生,硕士研究生,副主任技师,研究方向:肿瘤免疫分子生物学
更新日期/Last Update: 2010-05-28