[1]刘艳华),王玲),王彦平),等.膳食因素与肺癌关系的病例对照研究[J].郑州大学学报(医学版),2009,(06):1260-1262.
 LIU Yanhua),WANG Ling),WANG Yanping),et al.A casecontrol study on relationship between dietary intake and relative factors and lung cancer[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2009,(06):1260-1262.
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膳食因素与肺癌关系的病例对照研究()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2009年06期
页码:
1260-1262
栏目:
论著
出版日期:
2009-11-01

文章信息/Info

Title:
A casecontrol study on relationship between dietary intake and relative factors and lung cancer
作者:
刘艳华1)王玲1)王彦平1)耿振新2)马师2)陆维权3)吕全军1)#
1)郑州大学公共卫生学院营养与食品卫生学教研室 郑州 4500012)开封县卫生防疫站 开封 4710003)河南省肿瘤研究所 郑州 450003
Author(s):
LIU Yanhua1)WANG Ling1)WANG Yanping1)GENG Zhenxin2)MA Shi2)LU Weiquan3)LV Quanjun1)
1)Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou 4500012)Center for Disease Control and Prevention of Kaifeng County, Kaifeng 4751003)Henan Tumor Institute,Zhengzhou 450003
关键词:
肺癌膳食病例对照研究
Keywords:
lung cancerdietcasecontrol study
分类号:
R179
摘要:
探讨膳食及其相关因素与肺癌的关系。方法:应用病例对照研究的方法,选取开封县原发性肺癌病例130例,按性别、年龄11配对选取正常对照,问卷调查收集研究对象的一般情况、膳食摄入及相关情况,应用秩和检验和χ2检验进行单因素分析,应用logistic回归进行多因素分析,计算OR值及其95%可信区间(CI),筛选出肺癌的主要相关因素。结果:单因素分析发现8个暴露因素与肺癌发生有关;多因素分析发现饮食不规律(OR=5.032,95% CI 1.516~16.640)、肿瘤家族史(OR=8.569,95% CI 0.852~82.189)可能是肺癌的危险因素,经常摄入大米(OR=0.390, 95% CI 0.156~0.977)、体质指数大(OR=0.323,95% CI 0.122~0.879)及家庭月人均收入高(OR=0.394,95% CI 0.164~0.945)为肺癌的保护因素。结论:膳食及其相关因素中肺癌的保护因素和危险因素并存,合理膳食、规律饮食、保持理想的BMI和发展经济有助于降低肺癌的发生。
Abstract:
To investigate the relationship between dietary factors and lung cancer.Methods:The dietary intake and relative factors were investigated and compared between 130 cases (primary lung cancer patients) and 130 controls (matched for age and gender). The survey data were collected from well designed questionnaire. Statistical analysis of single factor and multivariate logistic regression were performed to screen the main risk factors of lung cancer.Results: During the single factor analysis,8 exposure factors were identified as relevant factors for lung cancer. The multivariate logistic regression result showed that irregular dietary behavior (OR=5.032, 95%CI=1.516~16.640) was a high risk factor of lung cancer and family history of tumor(OR=8.569,95%CI=0.852~82.189) was a potential risk factor. Consumption of rice (OR=0.390, 95%CI=0.156~0.977), body mass index(OR=0.323,95%CI=0.122~0.879) and average income per person in the family (OR=0.394,95%CI=0.164~0.945) were the protective factors against lung cancer.Conclusion: Some dietary factors and other relative elements are protective factors for lung cancer, but some are opposite. Healthy dietary behavior, ideal BMI value,and economic development might reduce the risk of primary lung cancer.

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备注/Memo

备注/Memo:
#通讯作者,男,1963年生,教授,研究方向:营养与疾病,Email:lqjnutr@zzu.edu.cn
更新日期/Last Update: 2010-05-14