[1]孙振涛),韩雪萍)#,苗丽君),等.氟比洛芬酯脂微球载体注射液超前镇痛用于老年患者术后镇痛效果[J].郑州大学学报(医学版),2010,(02):284-286.
 SUN Zhentao),HAN Xueping),MIAO Lijun),et al.Effects of preemptive analgesia for postoperative analgesia of flurbiprofen axetil injection in geriatric patients[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2010,(02):284-286.
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氟比洛芬酯脂微球载体注射液超前镇痛用于老年患者术后镇痛效果()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2010年02期
页码:
284-286
栏目:
论著
出版日期:
2010-03-30

文章信息/Info

Title:
Effects of preemptive analgesia for postoperative analgesia of flurbiprofen axetil injection in geriatric patients
作者:
孙振涛1)韩雪萍1)#苗丽君2)张卫1)
1)郑州大学第一附属医院麻醉科;河南省高等学校临床医学重点学科开放实验室郑州4500522)郑州大学第一附属医院呼吸科郑州450052
Author(s):
SUN Zhentao1)HAN Xueping1)MIAO Lijun2)ZHANG Wei1)
1)Department of Anesthesiology, the First Affiliated Hospital, Zhengzhou University;the Open Key Clinical Medical Experimental Laboratory Institute of Henan Province,Zhengzhou 4500522)Department of Respiratory Medicine, the First Affiliated Hospital, Zhengzhou University,Zhengzhou 450052
关键词:
氟比洛芬酯注射液老年人术后镇痛超前镇痛
Keywords:
flurbiprofen axetil injectiongeriatric patientpostoperative analgesiapreemptive analgesia
分类号:
R971.1
文献标志码:
A
摘要:
观察氟比洛芬酯脂微球载体注射液(凯纷)超前镇痛用于老年患者术后镇痛的效果及安全性。方法:ASAⅠ~Ⅱ级60~70岁腹部手术患者90例,随机分为3组各30例。A组于麻醉后、手术开始前10min缓慢静脉注射凯纷50mg,B组于术终缓慢静脉注射凯纷50mg,C组不给凯纷。3组均于手术结束前10min静脉滴注格拉司琼3mg,术后接静脉自控镇痛泵,泵内药物A组、B组为凯纷50mg+芬太尼8μg/kg+生理盐水(共100mL),C组为芬太尼10μg/kg+生理盐水(共100mL)。观察3组患者术后视觉模拟量表(VAS)镇痛评分、镇静评分、循环、呼吸、血氧饱和度及不良反应发生情况。结果:3组患者术后VAS镇痛评分比较,差异有统计学意义(F时间=1766.000,P<0.001;F组间=66.649,P<0.001)。3组患者术后均无过度镇静,3组患者术后镇静评分比较,差异无统计学意义(F组间=1.164,P=0.371),各时间点比较,差异有统计学意义(F时间=375.400,P<0.001)。3组患者术后循环、呼吸及血氧饱和度均在正常范围,均无不良反应发生。结论:氟比洛芬酯脂微球载体注射液超前镇痛效果良好,能有效缓解老年患者术后疼痛,无明显不良反应。
Abstract:
flurbiprofen axetil injection;geriatric patient;postoperative analgesia;preemptive analgesia

参考文献/References:

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备注/Memo

备注/Memo:
#通讯作者,女,1958年生,硕士,主任医师,研究方向:麻醉、疼痛治疗的基础与临床
更新日期/Last Update: 2010-04-29