[1]单国用△,刘兴安,张松,等.食管鳞状细胞癌组织中自噬基因 Beclin 1蛋白的表达[J].郑州大学学报(医学版),2010,(03):366-367.
 SHAN Guoyong,LIU Xingan,ZHANG Song,et al.Expression of Beclin 1 protein in esophageal squamous cell carcinoma tissue[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2010,(03):366-367.
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食管鳞状细胞癌组织中自噬基因 Beclin 1蛋白的表达()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2010年03期
页码:
366-367
栏目:
食管癌研究
出版日期:
2010-05-15

文章信息/Info

Title:
Expression of Beclin 1 protein in esophageal squamous cell carcinoma tissue
作者:
单国用刘兴安张松侯继院
郑州人民医院放疗科郑州450014
Author(s):
SHAN GuoyongLIU Xing’anZHANG SongHOU Jiyuan
Department of Radiation Oncology, Zhengzhou People’s Hospital, Zhengzhou 450014
关键词:
自噬Beclin 1食管肿瘤鳞状细胞癌
Keywords:
autophagyBeclin 1esophageal neoplasmsquamous cell carcinoma
分类号:
R735.1
摘要:
探讨食管鳞状细胞癌组织中 Beclin 1蛋白的表达与临床病理因素之间的关系。方法:应用免疫组织化学SP法检测50例食管鳞状细胞癌和其中30例相应的癌旁正常食管上皮组织中Beclin 1蛋白的表达。 结果:30例正常食管上皮组织中Beclin 1阳性表达率为100%,高于食管鳞状细胞癌组织的30%(9/30)(χ2=19.050,P<0.001)。50例食管鳞状细胞癌组织中Beclin 1蛋白的表达与淋巴结转移和病理分期有关(χ2分别为13.286,4.836,P均<0.05)。结论:Beclin 1与食管鳞状细胞癌的发生发展有关。
Abstract:
To evaluate Beclin 1 protein expression and its clinicopathological significance in esophageal squamous cell carcinoma tissue.Methods:A total of 50 cases of esophageal squamous cell carcinoma tissue and 30 cases of corresponding normal esophageal tissue were collected to detect the expression of Beclin 1 protein by immunohistochemistry,and the relationship between the expression of Beclin 1 and the clinicopathological factors of esophageal squamous cell carcinoma tissue was statistically analyzed.

参考文献/References:

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备注/Memo

备注/Memo:
△男,1971年6月生,硕士,副主任医师,研究方向:肿瘤放疗
更新日期/Last Update: 2010-05-28