[1]李志猛),乔军波),张谢夫)#,等.胃癌组织中Pokemon和半乳糖凝集素3蛋白的表达[J].郑州大学学报(医学版),2010,(03):460-462.
 LI Zhimeng),QIAO Junbo),ZHANG Xiefu),et al.Expression of Pokemon and Galectin3 proteins in gastric carcinoma tissue[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2010,(03):460-462.
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胃癌组织中Pokemon和半乳糖凝集素3蛋白的表达()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2010年03期
页码:
460-462
栏目:
论著
出版日期:
2010-05-15

文章信息/Info

Title:
Expression of Pokemon and Galectin3 proteins in gastric carcinoma tissue
作者:
李志猛1)乔军波2)张谢夫1)#赵春临1)
1)郑州大学第一附属医院普外科;河南省高等学校临床医学重点学科开放实验室郑州4500522)河南省人民医院血管瘤外科郑州450003
Author(s):
LI Zhimeng1)QIAO Junbo2)ZHANG Xiefu1)ZHAO Chunlin1)
关键词:
Pokemon半乳糖凝集素3胃癌
Keywords:
Pokemon Galectin3 gastric carcinoma
分类号:
R735.2
摘要:
检测胃癌组织中Pokemon和半乳糖凝集素3(Galectin3)蛋白的表达情况。方法:采用免疫组织化学SP法检测76例胃癌组织和16例正常胃黏膜组织中Pokemon和Galectin3 的表达,并分析其与临床病理特征的关系。结果:胃癌组织中Pokemon蛋白阳性表达率为59.2%(45/76),Galectin3蛋白阳性表达率为82.9%(63/76),均高于正常胃黏膜组织的18.8%(3/16)和12.5%(2/16)(χ2=8.671,P=0.003;χ2=28.284,P<0.001)。胃癌组织中Pokemon与Galectin3的阳性表达与淋巴结转移(χ2分别为10.787和11.626,P均=0.001)、pTNM分期(χ2=12.903,P<0.001;χ2=6.435,P=0.011)和浸润深度(χ2分别为11.849和11.701,P均=0.003)有关,且Pokemon与Galectin3表达有关联(χ2=5.253,rp=0.254,P=0.022)。结论:Pokemon及Galectin3与胃癌的侵袭、转移有关
Abstract:
To detect the expression of Pokemon and Galectin3 in gastric carcinoma tissue.Methods:The expressions of Pokemon and Galectin3 of 76 cases of gastric carcinoma tissue and 16 cases of normal gastric mucosa tissue were detected by immunohistochemical staining, and the relation with clinicopathologic characteristics was analysed

参考文献/References:

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备注/Memo

备注/Memo:
#通讯作者,男,1957年3月生,本科,教授,研究方向:胃肠外科,Email:zhangxiefu@medmail.com.cn
更新日期/Last Update: 2010-05-28