[1]赵倩△,边爱平,王春芳. 子宫内膜异位症患者内膜组织中Livin和Smac蛋白的表达[J].郑州大学学报(医学版),2011,(02):228.
 ZHAO Qian,BIAN Aiping,WANG Chunfang. Expression of Livin and Smac protein in endometrium of endometriosis patients[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2011,(02):228.
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 子宫内膜异位症患者内膜组织中Livin和Smac蛋白的表达()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2011年02期
页码:
228
栏目:
论著
出版日期:
2011-03-20

文章信息/Info

Title:
 Expression of Livin and Smac protein in endometrium of endometriosis patients
作者:
 赵倩△边爱平王春芳
 郑州大学第三附属医院妇产科 郑州 450052
Author(s):
  ZHAO QianBIAN AipingWANG Chunfang
 
Department of Obstetrics and Gynecology,the Third Affiliated Hospital,Zhengzhou University,Zhengzhou 450052
关键词:
 子宫内膜异位症LivinSmac
分类号:
R737.3
文献标志码:
A
摘要:
 目的:探讨凋亡抑制蛋白Livin和促凋亡蛋白Smac在子宫内膜异位症患者内膜组织中的表达情况及二者之间的关系。方法:采用免疫组织化学SP法检测在位内膜(A组)、异位内膜(B组)和正常子宫内膜(C组)组织(各30例)中Livin和Smac蛋白的表达。结果:①Livin在A、B、C组的相对表达量分别为(142.55±36.27)、(141.69±26.61)和(113.26±10.22),Smac在3组的相对表达量分别为(114.76±10.68)、(112.41±8.84)和(143.73±10.83),差异均有统计学意义(F=16.465和14.708,P均<0.05)。②A、B组中Livin和Smac蛋白的表达存在负相关(r=-0.552和-0.397,P均<0.001)。③Smac在A组增生期和分泌期的相对表达量分别为(118.23±24.69)和(124.07±21.31),差异无统计学意义(t=0.645,P=0.510),在C组增生期和分泌期的相对表达量分别为(150.93±3.04)和(159.18±13.20),差异有统计学意义(t=1.982,P=0.043);Livin在A、C组增生期(141.63±36.69,112.01±8.93)和分泌期(143.75±37.16,115.13±12.07)表达差异均无统计学意义(t=0.178和0.794,P均>0.05)。结论:Livin和Smac蛋白可能在子宫内膜异位症的发生中起到一定的作用。

参考文献/References:

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备注/Memo

备注/Memo:
 △女,1969年10月生,硕士,副主任医师,研究方向:普通妇科;Email:zhaoqianyx@163.com
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