[1]崔可飞△,滑少华,贺晓,等.定量超声弹性成像技术对单发甲状腺结节的鉴别诊断[J].郑州大学学报(医学版),2011,(05):709-63.
 CUI Kefei,HUA Shaohua,HE Xiao,et al.Differential diagnosis of quantitative ultrasound elasticity imaging for solitary thyroid nodules[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2011,(05):709-63.
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定量超声弹性成像技术对单发甲状腺结节的鉴别诊断
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2011年05期
页码:
709-63
栏目:
论著
出版日期:
2011-09-20

文章信息/Info

Title:
Differential diagnosis of quantitative ultrasound elasticity imaging for solitary thyroid nodules
作者:
崔可飞滑少华贺晓周元媛秦石成
郑州大学第一附属医院超声科 郑州 450052
Author(s):
CUI KefeiHUA ShaohuaHE XiaoZHOU YuanyuanQIN Shicheng
Department of Ultrasound, the First Affiliated Hospital, Zhengzhou University,Zhengzhou 450052
关键词:
超声弹性成像甲状腺结节相对硬度鉴别诊断
Keywords:
ultrasound elasticity imagingthyroid nodulesrelative hardnessdifferential diagnosis
分类号:
R653
摘要:
目的:探讨定量超声弹性成像技术对单发甲状腺结节的鉴别诊断价值。方法:162个单发甲状腺结节经病理分析,结节性甲状腺肿105个,腺瘤26个,腺癌31个,采用定量超声弹性成像技术检测其相对硬度,绘制ROC曲线。结果:结节性甲状腺肿、甲状腺腺瘤及癌的相对硬度分别为(1.191±0.208)、(1.326±0.295)和(2.094±0.754),3者比较,差异有统计学意义(F=68.360,P<0.001);甲状腺癌的相对硬度高于结节性甲状腺肿及甲状腺腺瘤(P<0.001),后两者差异无统计学意义(P>0.05)。以结节相对硬度诊断甲状腺良、恶性病变的ROC曲线下面积为0.901;以1.622作为界点,其敏感性、特异性及准确性分别为82.50%、95.40%和92.59%。结论:定量超声弹性成像技术对单发结节性甲状腺肿与甲状腺腺瘤的鉴别诊断能力不高,但对甲状腺癌具有很高的诊断价值。
Abstract:
Aim:To research the differential value of quantitative ultrasound elasticity imaging for solitary thyroid nodules.Methods:Quantitative ultrasound elasticity imaging was used to detect the relative hardness of thyroid nodules from 162 patients with solitary thyroid nodules. ROC curve was also used to distinguish benign and malignant thyroid nodules according to the relative hardness.Results: There were significant difference in the relative hardness among solitary thyroid nodules,thyroid adenoma,and solitary thyroid cancer (F=68.360,P<0.001). The relative hardness of solitary thyroid cancer(2.094±0.754) was higher compared with those of solitary thyroid nodules(1.191±0.208) and thyroid adenoma(1.326±0.295) (P<0.001). Area under ROC curve for the differential diagnosis on benign and malignant lesions was 0.901.When the dividing value was 1.682,the sensitivity, specificity and accuracy for the differential diagnosis of quantitative ultrasound elasticity imaging was 82.50%,95.40% and 92.59%.Conclusion: The differential diagnosis abilities of quantitative ultrasound elasticity imaging for solitary thyroid nodules and thyroid adenoma is not remarkable, but very significant for solitary thyroid cancer.

参考文献/References:

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备注/Memo

备注/Memo:
△女,1963年5月生,副教授,研究方向:甲状腺及乳腺疾病的超声诊断,Email:dzjhyd@126.com
更新日期/Last Update: 2011-09-20