[1]巴庆华,滕军放#,赵莘瑜,等.短暂性脑缺血发作患者血浆Hcy和血清胱抑素C水平分析[J].郑州大学学报(医学版),2011,(05):751.
 BA Qinghua,TENG Junfang,ZHAO Xinyu,et al.Levels of plasma homocysteine and serum cystatin C in transient ischemic attack patients[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2011,(05):751.
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短暂性脑缺血发作患者血浆Hcy和血清胱抑素C水平分析
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2011年05期
页码:
751
栏目:
论著
出版日期:
2011-09-20

文章信息/Info

Title:
Levels of plasma homocysteine and serum cystatin C in transient ischemic attack patients
作者:
巴庆华滕军放#赵莘瑜温丽君冯树涛
郑州大学第一附属医院神经内科 郑州 450052
Author(s):
BA QinghuaTENG JunfangZHAO XinyuWEN LijunFENG Shutao
Department of Neurology,the First Affiliated Hospital,Zhengzhou Universtity,Zhengzhou 450052
关键词:
短暂性脑缺血发作同型半胱氨酸胱抑素C
Keywords:
transient ischemic attack homocysteinecystatin C
分类号:
R743
摘要:
目的:探讨血浆同型半胱氨酸 (Hcy)、血清胱抑素C (CysC)与短暂性脑缺血发作(TIA)的关系。方法:分别测定101例TIA患者和64例健康体检者血浆Hcy(荧光偏振免疫分析法)和血清CysC水平(乳胶颗粒增强免疫比浊法)。结果:TIA组Hcy、CysC水平均高于对照组(t=3.459、3.167,P<0.01)。TIA患者CysC水平与Hcy呈弱相关(r=0.260,P=0.002)。logistic回归模型显示CysC(OR=1.311,95% CI=1.050~1.831)、Hcy(OR=1.123,95% CI=1.036~1.217)为TIA发病的危险因素。结论:TIA患者血浆CysC与血清Hcy水平升高可能均为TIA发病的危险因素。
Abstract:
Aim:To explore the changes of plasma homocysteine(Hcy) and serum cystatin C (CysC) in transient ischemic attack (TIA) patients.Methods:Contents of plasma Hcy and serum CysC of 101 TIA patients and 64 healthy subjects were determined using chemiluminescence and turbidimetric immunoassay,respectively.Results:Compared with healthy subjects,concentrations of plasma Hcy and serum CysC increased significantly in TIA patients (t=3.459,3.167,P<0.01). CysC showed a remarkable positive correlation to Hcy in TIA patients (r=0.260,P<0.05). Logistic regression showed that Hcy(OR=1.123,95% CI=1.036~1.217) and CysC(OR=1.311,95% CI=1.050~1.831) were risk factors of TIA.Conclusion:It is suggested both the increase of plasma Hcy and serum CysC may be the risk factors of TIA.

参考文献/References:

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备注/Memo

备注/Memo:
#通讯作者,男,1960年11月生,本科,主任医师,研究方向:脑血管病,Email:ltj.f6666@yahoo.com.cn
更新日期/Last Update: 2011-09-20