[1]王贺永△,吴丽丽,张淑青,等.彻底消毒前后神经内科病房病原菌构成及耐药性检测[J].郑州大学学报(医学版),2011,(05):756.
 WANG Heyong,WU Lili,ZHANG Shuqing,et al.Changes of pathogens distribution and antibiotic resistance in neurology ward after thorough disinfection[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2011,(05):756.
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彻底消毒前后神经内科病房病原菌构成及耐药性检测
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2011年05期
页码:
756
栏目:
论著
出版日期:
2011-09-20

文章信息/Info

Title:
Changes of pathogens distribution and antibiotic resistance in neurology ward after thorough disinfection
作者:
王贺永1吴丽丽2张淑青1李宏芬1沈志霞1
1)唐山市开滦医院检验科 唐山063000 2)唐山市协和医院检验科 唐山063000
Author(s):
WANG Heyong1WU Lili2ZHANG Shuqing1LI Hongfen1SHEN Zhixia1
1)Clinical Laboratory,Kailuan Hospital,Tangshan 063000 2)Clinical Laboratory,Tangshan Xiehe Hospital,Tangshan 063000
关键词:
病原菌抗生素耐药分析院内感染
Keywords:
bacteriaantibioticdrug resistancenosocomial infection
分类号:
R197.32
摘要:
目的:观察神经内科病房彻底消毒前后病原菌构成与耐药性的变化,为院内感染的防治提供理论依据。方法:对神经内科病房进行彻底消毒并空闲至少3个月后,只收新患者,并严格按照院内感染防治方法进行管理,标本按常规方法留取,送检。采用法国梅里埃VITEK2compact自动微生物鉴定仪进行菌株鉴定与药敏测定。结果:消毒后病原菌检出数量由484株减少为219株,菌株来源、病原菌构成有很大变化(χ2=18.140、92.270,P均<0.05),临床分离的病原菌仍以革兰阴性杆菌为主。消毒后耐药分布也发生了较大改变。结论:全面、彻底消毒是减少院内感染的有效措施,但抗生素的选择仍面临巨大挑战。
Abstract:
Aim: To analyze the pathogen distribution and antibiotic resistance in neurology ward.Methods:The neurology ward was thoroughly disinfected and idled for at least 3 months before accepting the first patient,and was in strict accordance with the management of nosocomial infection control methods. The pathogens from specimens were isolated and cultivated, as well as identified and classified with VITEK2compact automatic system.Results:The number of pathogen reduced from 484 to 219 after disinfection,the source and distribution of pathogen changed significantly(χ2=18.140,92.270,P<0.05). Gramnegative bacilli were the most common bacteria.Conclusion:A thorough disinfection is an effective measure to reduce nosocomial infections, however, the choice of antibiotics is still facing great challenges.

参考文献/References:

[1]罗彦丽.综合ICU病房10年间病菌构成及耐药性变迁分析[J].中国现代医药杂志,2009,11(1):85
[2]刘智成.脑卒中患者医院感染经济损失的对照调查分析[J].现代医药卫生,2008,24(22):3366
[3]葛庆岗,汪宗昱,阴赪宏,等.重症监护病房非发酵革兰阴性杆菌耐药性变迁[J].中国医院感染学杂志,2009,19(16):2188
[4]Pujol M, Pena C, Pallares R, et al. Nosocomial staphylococcus aureus bactermia among nasal carriers of methicillinresistant and methicillinsusceptible strains [J]. Am J Med, 1996, 100(5):509

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备注/Memo

备注/Memo:
△男,1976年6月生,硕士,主管检验技师,研究方向:微生物学与免疫学,Email:383102702@qq.com
更新日期/Last Update: 2011-09-20