[1]王军,朱登纳.基因工程神经干细胞治疗缺氧缺血性脑损伤研究进展[J].郑州大学学报(医学版),2011,(06):813.
点击复制

基因工程神经干细胞治疗缺氧缺血性脑损伤研究进展
分享到:

《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2011年06期
页码:
813
栏目:
特约述评
出版日期:
2011-11-20

文章信息/Info

作者:
王军朱登纳
郑州大学第三附属医院小儿脑瘫康复中心 郑州 450052
关键词:
新生儿缺氧缺血性脑损伤神经干细胞基因工程

参考文献/References:

[1]Lee JA,Kim BI,Jo CH,et al.Mesenchymal stemcell transplantation for hypoxicischemic brain injury in neonatal rat model[J]. Pediatr Res,2010,67(1):42
[2]Paula S, Greggio S, DaCosta JC.Use of stem cells in perinatal asphyxia: from bench to bedside[J]. J Pediatr (Rio J),2010,86(6):451
[3]Lee IS, Jung K,Kim M,et al.Neural stem cells: properties and therapeutic potentials for hypoxicischemic brain injury in newborn infants[J].Pediatr Int,2010,52(6):855
[4]Svman K,Brown KL.Treating neonatal brain injurypromise and inherent research challenges[J].Recent Pat Inflamm Allergy Drug Discov,2010,4(1):16
[5]王晓莉,杨于嘉,王庆红,等.不同时间窗高压氧治疗对HIBD新生大鼠脑白质损伤的影响[J].中国当代儿科杂志, 2007, 9(4):308
[6]States RA, Salem Y, Pappas E. Overground gait training for individuals with chronic stroke: a Cochrane systematic review[J].J Neurol Phys Ther,2009,33(4):179
[7]Marion D, Bullock MR. Current and future role of therapeutic hypothermia[J].J Neurotrauma,2009,26(3):455
[8]Fatemi A, Wilson MA, Johnston MV. Hypoxicischemic encephalopathy in the term infant[J].Clin Perinatol,2009,36(4):835
[9]Okano H. Neural stem cells and strategies for the regeneration of the central nervous system[J].Proc Jpn Acad Ser B Phys Biol Sci,2010,86(4):438
[10]王军,范亚珍,陈海,等.脐血单个核细胞诱导的神经干细胞中 Foxg1和 Nestin基因表达及其相互关系[J].实用儿科临床杂志,2010,25(11):848
[11]朱登纳,张博爱,王军,等.脐血源性神经干细胞移植对缺血缺氧性脑损伤新生大鼠的治疗作用[J].江苏医药,2010,36(24):2932
[12]屈素清,栾佐,刘卫鹏,等.人神经干细胞移植治疗脑性瘫痪并重度视觉障碍患儿的疗效[J].实用儿科临床杂志,2009,24(10):771
[13]Liang W, Han Q, Jin W, et al. The promotion of neurological recovery in the rat spinal cord crushed injury model by collagenbinding BDNF[J].Biomaterials,2010,31(33):8634
[14]Anton R, Kordower JH, Maidment NT, et al.Neuraltargeted gene therapy for rodent and primate hemiparkinsonism[J].Exp Neurol,1994,127(2):207
[15]Gu S, Huang H, Bi J, et al. Combined treatment of neurotrophin3 gene and neural stem cells is ameliorative to behavior recovery of Parkinson’s disease rat model[J].Brain Res,2009,1257:1
[16]An SS, Jin HL, Kim KN, et al. Neuroprotective effect of combined hypoxiainduced VEGF and bone marrowderived mesenchymal stem cell treatment[J].Childs Nerv Syst, 2010, 26(3):323
[17]Chen B, Gao XQ, Yang CX, et al. Neuroprotective effect of grafting GDNF genemodified neural stem cells on cerebral ischemia in rats[J]. Brain Res, 2009, 1284:1
[18]王军,吴值荣,朱登纳,等.人胰岛素样生长因子1基因质粒载体的构建及其在人脐血源性神经干细胞中的表达[J].实用儿科临床杂志,2011,26(6):448
[19]朱登纳, 贾延劼, 王军, 等.人胰岛素样生长因子1修饰的神经干细胞移植对缺氧缺血性脑损伤新生大鼠的治疗作用[J].实用儿科临床杂志,2011,26(16):1279
[20]范亚珍,王军,陈海,等.脐血单个核细胞体外向神经干细胞的诱导及 Foxg1基因的表达[J].山东医药,2010,50(11):13
[21]朱登纳,贾延劼,王军,等.人脐血MSCs向神经元样细胞分化过程中Neurogenin1的表达变化[J].中国病理生理杂志,2011,27(5):996
[22]Englund U, FrickerGates RA, Lundberg C, et al. Transplantation of human neural progenitor cells into the neonatal rat brain: extensive migration and differentiation with longdistance axonal projections[J].Exp Neurol,2002,173(1):1
[23]Park KI.Transplantation of neural stem cells: cellular & gene therapy for hypoxicischemic brain injury[J].Yonsei Med J, 2000, 41(6):825
[24]Pendharkar AV, Chua JY, Andres RH,et al. Biodistribution of neural stem cells after intravascular therapy for hypoxicischemia[J]. Stroke, 2010, 41(9):2064
[25]Willing AE, Lixian J, Milliken M,et al. Intravenous versus intrastriatal cord blood administration in a rodent model of stroke[J]. J Neurosci Res, 2003, 73(3):296
[26]Suzuki SO,Goldman JE. Multiple cell populations in the early postnatal subventricular zone take distinct migratory pathways: a dynamic study of glial and neuronal progenitor migration[J].J Neurosci,2003,23(10):4240
[27]Veizovic T,Beech JS,Stroemer RP,et al.Resolution of stroke deficits following contralateral grafts of conditionally immortal neuroepithelial stem cells[J].Stroke,2001,32(4):1012
[28]Hofstetter CP,Schwarz EJ,Hess D,et al.Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery[J].Proc Natl Acad Sci USA,2002,99(4):2199

相似文献/References:

[1]白蓉)△,贾延劼)#,白宏英).骨髓基质细胞移植治疗新生大鼠缺氧缺血性脑损伤效果观察*[J].郑州大学学报(医学版),2009,(04):754.
 BAI Rong),JIA Yanjie),BAI Hongying).Effects of bone marrow stromal cell transplantation on hypoxic ischemic brain damage in neonatal rats[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2009,(06):754.
[2]周超,王佳,陈萍萍,等.脐血清与临产妇血清钙、铁、锌含量与新生儿身长的关系[J].郑州大学学报(医学版),2009,(04):856.
 ZHOU Chao,WANG Jia,CHEN Pingping,et al.Relationships between the mineral contents in the cord serum and the pregnant woman’s serum and newborn’s body length[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2009,(06):856.
[3]赵娜,王旗,陈萍萍,等.临产妇血清与脐血清钙、铁、锌水平与新生儿出生体质量的关系[J].郑州大学学报(医学版),2009,(04):858.
 ZHAO Na,WANG Qi,CHEN Pingping,et al.Relationships between the level of mineral in pregnant women’s serum and umbilical cord blood and newborn’s birth weight[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2009,(06):858.
[4]蒋洪燕.纳洛酮联合脑活素治疗新生儿缺氧缺血性脑病60例[J].郑州大学学报(医学版),2010,(04):686.
 [J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2010,(06):686.
[5]孙慧清,康文清,熊虹.高频振荡通气治疗新生儿呼吸衰竭31例[J].郑州大学学报(医学版),2010,(04):698.
 [J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2010,(06):698.
[6]刘付东),温世宝),朱彩荣),等. 产妇血清叶酸水平对新生儿出生特征的影响*[J].郑州大学学报(医学版),2011,(02):208.
 LIU Fudong),WEN Shibao),ZHU Cairong),et al. Effects of maternal serum folic acid levels on birth characteristics of offspring[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2011,(06):208.
[7]闫安平,刘艳红,聂春霞.高频振荡通气辅助治疗新生儿持续肺动脉高压效果[J].郑州大学学报(医学版),2011,(04):650.
[8]王军△,尚凤伟,朱登纳,等.银杏内酯B对缺氧缺血性脑损伤新生大鼠脑组织Caspase3及VEGF mRNA表达的影响*[J].郑州大学学报(医学版),2013,(02):175.
 WANG Jun,SHANG Fengwei,ZHU Dengna,et al.Effects of ginkgolide B on expression of Caspase3 and VEGF mRNA in brain tissue of newborn rats with hypoxicischemic brain damage[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2013,(06):175.
[9]贺同坤),周郭育),王 佳),等.岭回归法分析孕期郑州市大气污染物暴露与新生儿出生形态特征的关系[J].郑州大学学报(医学版),2018,(03):294.[doi:10.13705/j.issn.1671-6825.2017.10.102]
 HE Tongkun),ZHOU Guoyu),WANG Jia),et al.Association between birth characteristics and ambient air pollution during maternal pregnancy in Zhengzhou by ridge regression[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2018,(06):294.[doi:10.13705/j.issn.1671-6825.2017.10.102]

备注/Memo

备注/Memo:
王军,女,汉族,1963年7月生,儿科教授、主任医师、博士研究生导师。任郑州大学第三附属医院业务副院长和河南省小儿脑瘫康复治疗中心主任,为河南省教育厅学术技术带头人、河南省优秀教师、河南省优秀医师、郑州市医德标兵。目前担任河南省医学会理事会理事、河南省红十字会理事会理事、郑州市医学会理事会理事、河南省预防医学会儿童脑瘫预防与康复专业委员会主任委员、河南省医院药事管理专业委员会副主任委员、中华医学会河南省儿科学会常委、中国医师协会康复医师分会常委、中国残疾人康复协会小儿脑瘫康复专业委员会常委、中华医学会河南省康复医学与物理医学专业委员会常委、《郑州大学学报(医学版)》审稿人和《河南医学研究》杂志编委。从事小儿内科和小儿脑瘫康复工作26 a,获各类科技进步奖6项,承担省科委、教委科研课题8项,撰写和参编专业书籍11部,已发表学术论文56篇。主要研究方向为小儿神经系统疾病尤其是小儿脑瘫康复。
更新日期/Last Update: 1900-01-01