[1]娄华,孙丽君,王兴玲#,等.玻璃化冷冻法对冻融胚胎移植周期结局的影响[J].郑州大学学报(医学版),2011,(06):891.
 LOU Hua,SUN Lijun,WANG Xingling,et al.Effects of vitrification methods on clinical outcome of frozenthawed embryo transfer[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2011,(06):891.
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玻璃化冷冻法对冻融胚胎移植周期结局的影响
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2011年06期
页码:
891
栏目:
论著
出版日期:
2011-11-20

文章信息/Info

Title:
Effects of vitrification methods on clinical outcome of frozenthawed embryo transfer
作者:
娄华孙丽君 王兴玲#郝大勇王雪梅于晓娜
郑州大学第三附属医院生殖中心 郑州 450052
Author(s):
LOU Hua SUN Lijun WANG Xingling HAO DayongWANG XuemeiYU Xiaona
Reproductive Medicine Center,the Third Affiliated Hospital,Zhengzhou University, Zhengzhou 450052
关键词:
玻璃化冷冻程序化慢速冷冻胚胎完整率安全性
Keywords:
vitrificationslowfreezing methodblastomere integrity ratesafety
分类号:
R714.2
摘要:
目的:探讨玻璃化冷冻法对冻融胚胎移植周期结局的影响。方法:对324个玻璃化冷冻人卵裂期胚胎复苏周期和146个程序化慢速冷冻胚胎复苏周期进行分析,比较2组冷冻胚胎复苏后的存活率、完整率、种植率、临床妊娠率、孕周、新生儿身高及体质量等指标。结果:玻璃化冷冻组的胚胎完整率、临床妊娠率均高于程序化慢速冷冻组(83.24% vs 47.54%,χ2=179.772,P<0.001;37.38% vs 27.66%,χ2=4.073,P=0.044);2组流产率、分娩孕周、新生儿出生体质量及身高比较,差异无统计学意义(P均>0.05)。结论:玻璃化冷冻胚胎较程序化慢速冷冻法有更高的复苏胚胎完整率及临床妊娠率,可在临床上安全应用。
Abstract:
Aim:To investigate the effects of vitrification methods on the clinical outcome of frozenthawed embryo transfer.Methods:A statistical analysis was performed on 324 vitrification cycles and 146 slowfreezing cycles.After warming, the survival rate, blastomere integrity rate, implantation rate,clinical pregnancy rate,gestational weeks,newborn weight and height were evaluated and compared between the two methods.Results:The blastomere integrity rate and clinical pregnancy rate by vitrification were significantly higher than those by slowfreezing method(83.24% vs 47.54%,χ2=179.772,P<0.001;37.38% vs 27.66%,χ2=4.073,P=0.044).There were no significant differences between the two methods in the miscarriage rate, gestational weeks, newborn weight and height (P>0.05),respectively.Conclusion:Vitrification provides a higher blastomere integrity and clinical pregnancy rate than slowfreezing method.It could be safe in clinical application.

参考文献/References:

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备注/Memo

备注/Memo:
#通讯作者,女,1964年2月生,硕士,主任医师,研究方向:生殖内分泌,Email:wangxl208@sohu.com
更新日期/Last Update: 1900-01-01