[1]王小泉),张沛),梁菁),等.伴冠心病牙周炎患者牙周临床指标和血清TNFα的分析*[J].郑州大学学报(医学版),2012,(03):356.
 WANG Xiaoquan),ZHANG Pei),LIANG Jing),et al.Testing of periodontal clinical indicators and serum TNFα level in periodontal patients with coronary heart disease[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2012,(03):356.
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伴冠心病牙周炎患者牙周临床指标和血清TNFα的分析*
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2012年03期
页码:
356
栏目:
应用研究
出版日期:
2012-05-20

文章信息/Info

Title:
Testing of periodontal clinical indicators and serum TNFα level in periodontal patients with coronary heart disease
作者:
王小泉1)张沛2)梁菁2)黄彬2)吴宏超3)李力4)轩东英1)赵红宇5)#章锦才1)
1)南方医科大学附属口腔医院,广东省口腔医院牙周科 广州 510280 2)郑州大学口腔医学院 郑州 450052 3)南方医科大学珠江医院心血管内科 广州 510280 4)广州市番禺疗养院 番禺 511400 5)南方医科大学附属口腔医院,广东省口腔医院番禺分院牙周科 番禺 511400
Author(s):
WANG Xiaoquan1)ZHANG Pei2)LIANG Jing2)HUANG Bin2)WU Hongchao3)LI Li4)XUAN Dongying1)ZHAO Hongyu5)ZHANG Jincai1)
1)Department of Periodontal, Guangzhou 510280 2)School of Stomatology,Zhengzhou 450052 3)Department of Internal MedicineCardiovascular, Guangzhou 510280 4)Guangzhou Panyu Sanatorium,Panyu 511400 5)Department of Periodontal,Panyu 511400
关键词:
牙周炎冠心病肿瘤坏死因子α
Keywords:
periodontitis coronary heart disease TNFα
分类号:
R781.4
摘要:
目的:分析伴冠心病牙周炎患者的牙周临床检查指标及血清肿瘤坏死因子α(TNFα)水平,为牙周炎与冠心病关系的研究提供实验依据。方法:44例伴冠心病牙周炎患者、48例慢性牙周炎患者和45例健康对照进入此项研究。对入选对象进行全面牙周检查,检测血清TNFα水平。结果:3组对象的血清TNFα水平、平均牙周探诊深度、平均牙龈附着丧失、平均龈沟出血指数均差异有统计学意义(F=49.424,274.630,1 051.612,303.041,P<0.001),伴冠心病牙周炎组的各项观测指标均高于慢性牙周炎组(P<0.05)。结论:冠心病可能会加重牙周局部炎症。
Abstract:
Aim:To analyze the periodontal clinical indicators and the serum level of tumor necrosis factorα(TNFα) of chronic periodontitis with coronary heart disease.Methods:A total of 44 cases of chronic periodontitis with coronary heart disease, 48 cases of chronic periodontitis,and 45 healthy controls were subjected to perform periodontal examinations and the measurement of serum levels of TNFα.Results:Among the three groups,there were significant differences in serum TNFα level, average probing depth,average attachment loss and average sulcus bleeding index (F=49.424,274.630,1 051.612,303.041,P<0.001).The results of the indexes mentioned above of the chronic periodontitis with coronary heart disease group were higher than those of chronic periodontitis group and healthy control group(P<0.05). Conclusion:Coronary heart disease may have some impacts on periodontal local inflammation.

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备注/Memo

备注/Memo:
*“十一?五”国家科技支撑计划基金资助项目2007BAI18B02;广东省自然科学基金资助项目9151026003000003 #通讯作者,女,1965年7月生,硕士,主任医师,研究方向:牙周炎与冠心病的相关性,Email:zhongyu93@163.com
更新日期/Last Update: 2012-05-31