[1]郭哲),史惠蓉)#.宫颈癌组织中CD13与CD34的表达[J].郑州大学学报(医学版),2012,(04):525.
 GUO Zhe,SHI Huirong.Expressions of CD13 and CD34 in cervical carcinoma tissue[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2012,(04):525.
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宫颈癌组织中CD13与CD34的表达
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2012年04期
页码:
525
栏目:
应用研究
出版日期:
2012-07-20

文章信息/Info

Title:
Expressions of CD13 and CD34 in cervical carcinoma tissue
作者:
郭哲1)史惠蓉2)#
1)南阳市中心医院妇产科 南阳 473000 2)郑州大学第一附属医院妇产科 郑州 450052
Author(s):
GUO Zhe1)SHI Huirong2)
1)Department of Gynecology and Obstetrics,the Central Hospital of Nanyang,Nanyang 473000 2)Department of Gynecology and Obstetrics,the First Affiliated Hospital,Zhengzhou University, Zhengzhou 450052
关键词:
宫颈癌微血管密度CD13CD34
Keywords:
cervical carcinomamicrovessel densityCD13CD34
分类号:
R737.33
摘要:
目的:探讨CD13与CD34标记宫颈癌微血管的意义。方法:60例宫颈癌组织中,FIGOⅠ期32例,Ⅱ期28例;鳞癌45例,腺癌15例;有盆腔淋巴结转移19例。应用免疫组化SP法检测CD13和CD34标记的宫颈癌组织中的微血管密度(MVD)。结果:Ⅱ期、有盆腔淋巴转移及病理类型为腺癌的宫颈癌组织中CD13标记的MVD高于Ⅰ期、无转移病理类型为及鳞癌者(t=5.673,11.541和3.041,P<0.05),而CD34标记的MVD与宫颈癌的分期、有无盆腔淋巴结转移及病理类型均无关(t=1.791,1.108和1.304,P>0.05)。结论:CD13标记的MVD可能更有助于宫颈癌患者的预后判断。
Abstract:
Aim:To explore the significance of detection of microvascular density(MVD) labelled by CD13 and CD34 in cervical cancer.Methods:A total of 60 cases of cervical cancer specimens were selected to detect MVD labelled by CD13 or CD34 using immunohistochemical SP method.Among the 60 cases,45 cases were squamous cell carcinoma(SCC) and 15 cases were adenocarcinoma, 32 cases were in FIGO Ⅰ stage and 28 cases were in Ⅱ stage,and 19 cases were with pelvic lymph node metastasis.Results:MVD marked by CD13 of cases in Ⅱ stage,or with pelvic lymph node metastasis,or with adenocarcinoma was higher than that of cases in Ⅰ stage,or without metastasis,or with SCC(t=5.673,11.541,and 3.041,P<0.05);while MVD marked by CD34 had no differences between Ⅰ and Ⅱ stage cases,and between cases with or without metastasis,SCC and adenocarcinoma (t=1.791,1.108,and 1.304,P>0.05).Conclusion:MVD marked by CD13 may provide more valuable information for cervical cancer prognosis.

参考文献/References:

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备注/Memo

备注/Memo:
#通讯作者,女,1956年4月生,博士,教授,研究方向:妇科肿瘤,Email:huirougshi@yahoo.com.cn
更新日期/Last Update: 2012-08-14