[1]梁琳琳△,李杭生,何巧花,等.IVF周期中不同亚型多囊卵巢综合征不孕患者低剂量递增促排卵效果*[J].郑州大学学报(医学版),2012,(04):530.
 LIANG Linlin,LI Hangsheng,HE Qiaohua,et al.Comparison of clinical results of lowdose increasing ovarian stimulation in IVF patients with different subtype of polycystic ovary syndrome[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2012,(04):530.
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IVF周期中不同亚型多囊卵巢综合征不孕患者低剂量递增促排卵效果*
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2012年04期
页码:
530
栏目:
应用研究
出版日期:
2012-07-20

文章信息/Info

Title:
Comparison of clinical results of lowdose increasing ovarian stimulation in IVF patients with different subtype of polycystic ovary syndrome
作者:
梁琳琳李杭生何巧花王璐张翠莲
河南省人民医院生殖中心 郑州 450003
Author(s):
LIANG LinlinLI HangshengHE QiaohuaWANG LuZHANG Cuilian
Reproductive Center, Henan Provincial People's Hospital,Zhengzhou 450003
关键词:
多囊卵巢综合征低剂量递增促排卵方案亚型体外受精
Keywords:
PCOS lowdose increasing ovarian stimulation subtype IVF
分类号:
R588.6
摘要:
目的:分析不同亚型多囊卵巢综合征(PCOS)不孕患者在体外受精胚胎移植(IVFET)治疗周期中,采用低剂量递增促排卵方案的临床治疗效果。方法:回顾性分析2006年5月至2010年4月按低剂量递增促排卵方案行IVFET治疗PCOS不孕患者共264周期,对患者按2003年鹿特丹标准分为3个亚型,Ⅰ型组86周期,Ⅱ型组157周期,Ⅲ型组21周期,比较各型实验室及临床相关指标的差异。结果:Ⅱ型组注射HCG日>14 mm卵泡数(10.9±5.8)、可利用胚胎率(65.9%)低于Ⅰ型组(15.9±7.3;73.4%)和Ⅲ型组(14.0±7.2;77.4%),差异有统计学意义(F=17.351,P<0.001;χ2=19.471,P<0.001);余临床及实验室结果以及妊娠结局差异无统计学意义。结论:低剂量递增促排卵方案是PCOS不孕患者有效的促排卵方案之一,不同亚型的PCOS患者临床结局相似。
Abstract:
Aim:To compare clinical results of lowdose increasing ovarian stimulation in IVF patients with different subtype of polycystic ovary syndrome(PCOS).Methods:The patients with PCOS (264 IVFET cycles) received lowdose increasing ovarian stimulation treatment in our center from May 2006 to April 2010 were retrospectively analyzed. Patients were divided into 3 subtypes according to Rotterdam Standard 2003. There were 86 cycles in type Ⅰ group,157 cycles in type Ⅱ group,and 21 cycles in type Ⅲ group. The laboratorial and clinical indicators in each subgroup were compared respectively.Results:The number of follicles>14 mm of subgroup Ⅱ(10.9±5.8) at HCG day, and the rate of acquired embryos in subgroup Ⅱ(65.9%)was lower than those in subgroup Ⅰ(15.9±7.3;73.4%) and subgroup Ⅲ(14.0±7.2;77.4%),and the differences were significant (F=17.351,P<0.001;χ2=19.471,P<0.001).The other clinical results and experiment results had no significant difference.Conclusion:Lowdose increasing ovarian stimulation can be used as an effective protocol in infertility patients with PCOS,and the clinical results are similar to patients with different subtypes of PCOS.

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备注/Memo

备注/Memo:
*郑州市科技局攻关基金资助项目112PPTSF295 △女,1980年7月生,博士,主治医师,研究方向:生殖医学,Email:llliang_doctor@126.com
更新日期/Last Update: 2012-08-14