[1]李仕群,朱静媛,李岩,等.沙颍河流域居民血清铅、镉、锌、铜及金属硫蛋白的测定*[J].郑州大学学报(医学版),2013,(06):788.
 LI Shiqun,ZHU Jingyuan,LI Yan,et al.Measurement and analysis of serum lead, cadmium, zinc, copper and metallothionein in residents of Shaying River area[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2013,(06):788.
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沙颍河流域居民血清铅、镉、锌、铜及金属硫蛋白的测定*
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2013年06期
页码:
788
栏目:
应用研究
出版日期:
2013-11-20

文章信息/Info

Title:
Measurement and analysis of serum lead, cadmium, zinc, copper and metallothionein in residents of Shaying River area
作者:
李仕群朱静媛李岩王志瑾 袁伟 程学敏巴月崔留欣#
郑州大学公共卫生学院劳动卫生学与环境卫生学教研室 郑州 450001
Author(s):
LI Shiqun ZHU Jingyuan LI Yan WANG Zhijin YUAN Wei CHENG Xuemin BA Yue CUI Liuxin
Department of Occupational and Environmental Health Sciences, College of Public Health, Zhengzhou University, Zhengzhou 450001
关键词:
水污染 血铅 血镉 金属硫蛋白
Keywords:
water pollution blood lead blood cadmium metallothionein
分类号:
R123.1
摘要:
目的:探讨沙颍河污染区外环境重金属暴露对居民血清铅、镉、锌、铜及金属硫蛋白(MT)的影响。方法:在距沙颍河河堤5 km以内和20 km以外各选取一个人口构成相似的村庄分别作为污染区和对照区,测量河水、饮用水、土壤、蔬菜和粮食中的铅、镉含量。采用火焰原子吸收光谱法测定河水、饮用水、土壤、蔬菜、粮食中的铅、镉含量;采用溶出伏安法测定各组人群血清中的铅、镉、锌、铜含量;采用ELISA方法测定人群血清中MT的含量。结果:污染区饮用水、土壤、粮食和蔬菜中的铅、镉含量均高于对照区(铅:t=2.663、2.300、3.001和2.117,P<0.05;镉:t=3.549、2.073、2.202和2.167,P<0.05);污染区人群的血清铅、镉水平和铜/锌比值高于对照区(t=5.544、10.438和5.556,P<0.05);血清MT含量随着血清铅、镉含量的增加而增加。结论:沙颍河水污染已影响到当地居民体内的重金属负荷。
Abstract:
Aim: To investigate the influence of heavy metal exposure of Shaying River area on the serum lead,cadmium, zinc, copper and metallothionein(MT)levels in residents of the area. Methods:Contaminated and control areas were chosen from villages less than 5 km and more than 20 km away from the Shaying River respectively, which had similar population composition and economy condition. The concentrations of lead and cadmium in drinking water, soil, grain and vegetables samples from the two areas were measured respectively by flame atomic absorption spectrometry. Serum lead, cadmium, zinc and copper levels were determined by cyclic voltammetry method. Serum MT level was measured by ELISA. Results: The levels of serum lead, cadmium in drinking water, soil, grain and vegetable samples in the contaminated area were significantly higher than those of control area(lead:t=2.663,2.300,3.001,and 2.117,P<0.05;cadmium:t=3.549,2.073,2.202,and 2.167,P<0.05). The levels of serum lead, cadmium, zinc, and Cu/Zn in the contaminated area were significantly higher than those of control area respectively(t=5.544,10.438,and 5.556,P<0.05). Conclusion: Water pollution of Shaying River has affected the load of heavy metals in local residents.

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备注/Memo

备注/Memo:
*国家“十二·五”重大水专项子课题 2009ZX07210-006-3-3
#通讯作者,男,1955年5月生,教授,研究方向:环境毒理学,E-mail:clx@zzu.edu.cn
更新日期/Last Update: 2013-11-20