[1]张月兰),张晓敏),赖道锋),等.不同正畸力作用下大鼠疼痛行为反应变化[J].郑州大学学报(医学版),2014,(03):377.
 ZHANG Yuelan,ZHANG Xiaomin,LAI Daofeng,et al.Pain related behavior response to experimental tooth movement in rats by different orthodontic forces[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2014,(03):377.
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不同正畸力作用下大鼠疼痛行为反应变化
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2014年03期
页码:
377
栏目:
应用研究
出版日期:
2014-05-20

文章信息/Info

Title:
Pain related behavior response to experimental tooth movement in rats by different orthodontic forces
作者:
张月兰12张晓敏1赖道锋1杨建浩1曲幸辉1刘林嶓2)#
1)郑州大学口腔医学院正畸科 郑州 4500522)郑州大学第一附属医院整形外科 郑州 450052
Author(s):
ZHANG Yuelan12ZHANG Xiaomin1LAI Daofeng1YANG Jianhao1QU Xinghui1LIU Linbo2
1)Department of Orthodontics, College of Stomatology,Zhengzhou University, Zhengzhou 4500522)Department of Plastic Surgery,the First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052
关键词:
正畸力大鼠疼痛行为
Keywords:
AbstractAim: To observe painrelated behavior response to experimental tooth movement by different orthodontic forces. Methods: A total of 78 8weekold male SD rats weighted (266.67±20.46) g were randomly allocated into control group and experimental gro
分类号:
R783.5
摘要:
摘要目的:观察不同正畸力作用下疼痛行为反应的变化。方法:选取78只8周龄、体重为(266.67±20.46) g的SD雄性大鼠,随机分为空白组6只和实验组(包括50 g力值组和100 g力值组)72只,空白组不做任何处理,实验组分别施加50和100 g力近中移动左侧上颌第一磨牙建立大鼠实验性牙齿移动模型,观察加力后1、2、3、5、7、14 d时的疼痛行为反应。结果:各组大鼠前30 s通过的总线数、5 min内通过的总线数、5 min内通过旷野中心的总线数、5 min内抬起行为的总时间、5 min内拭嘴行为的总时间及抗捕获行为评分比较,差异均有统计学意义(H=12.019、25.166、10.095、2.224、9.456、23.960,P均<0.05);且100 g力值组疼痛反应较50 g力值组重,2 d组后5项指标比较差异均有统计学意义(P均<0.05)。结论:正畸力作用下2 d时大鼠疼痛最严重,且疼痛的严重程度与所施加的正畸力值有关。
Abstract:
orthodontic force;rat;painrelated behavior

参考文献/References:

[1]Krukemeyer AM,Arruda AO,Inglehart MR. Pain and orthodontic treatment[J].Angle Orthod, 2009,79(6):1175 [2]侯旭,孙新华.实验性牙移动大鼠牙周组织环氧化酶2的表达及意义[J].吉林大学学报:医学版,2009,35(3):423 [3]Yozgatian JH,Zeredo JL,Hotokezaka H,et al.Emotional stress and painrelated behaviors evoked by experimental tooth movement[J].Angle Orthod,2008,78(3):487 [4]Yang Z,Wang Y,Luo W,et al.Trigeminal expression of NmethylDaspartate receptor subunit 1 and behavior responses to experimental tooth movement in rats[J].Angle Orthod,2009,79(5):951 [5]Andreasen GF,Zwanziger D.A clinical evaluation of the differential force concept as applied to the edgewise bracket[J].Am J Orthod,1980,78(1):25 [6]Ogura M,Kamimura H,AlKalaly A,et al.Pain intensity during the first 7 days following the application of light and heavy continuous forces[J].Eur J Orthod,2009,31(3):314

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备注/Memo

备注/Memo:
#通讯作者,男,1960年3月生,教授,研究方向:体表肿瘤,Email:liulinbo@zzu.edu.cn
更新日期/Last Update: 1900-01-01