[1]李辉)△,姜春霞),宁培刚),等.肺内孤立结节的高分辨CT征象诊断价值[J].郑州大学学报(医学版),2014,(06):872.
 LI Hui),JIANG Chunxia),NING Peigang),et al.Diagnostic value of sign of solitary pulmonary nodule in highresolution CT[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2014,(06):872.
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肺内孤立结节的高分辨CT征象诊断价值
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2014年06期
页码:
872
栏目:
应用研究
出版日期:
2014-11-20

文章信息/Info

Title:
Diagnostic value of sign of solitary pulmonary nodule in highresolution CT
作者:
李辉1)△姜春霞2)宁培刚3)阚晓静3)陈翠云3)武明辉3)冯敢生1)
1)武汉协和医院放射科 武汉 4300002)郑州大学学报编辑部 郑州 4500013)河南省人民医院放射科 郑州 450003
Author(s):
LI Hui1)JIANG Chunxia2)NING Peigang3)KAN Xiaojing3)CHEN Cuiyun3)WU Minghui3)FENG Gansheng1)
1)Department of Radiology, Wuhan Union Hospital, Wuhan 4300002)Editorial Board of Journal of Zhengzhou University,Zhengzhou 4500013)Department of Radiology, Henan Provincial People′s Hospital, Zhengzhou 450003
关键词:
CT结节诊断
Keywords:
CTlungnodulediagnosis
分类号:
R734.2
摘要:
目的:探讨肺内孤立结节(SPN)高分辨CT征象对于良恶性的鉴别诊断价值。方法:回顾性分析经病理学确诊的129例SPN(恶性结节88例,良性结节41例)的高分辨CT征象,对不同征象在良恶性SPN中的发生率进行比较,评价不同指标的诊断敏感度、特异度及准确率。 结果:恶性SPN的CT征象中前3位依次为毛刺征、分叶征和血管集束征,均高于在良性SPN中的发生率(χ2=26.590、33.661和5.125,P均<0.05)。当选择毛刺征、分叶征和血管集束征3种征象中的任意3个联合进行良恶性鉴别诊断时,毛刺征和分叶征联合指标的鉴别诊断敏感度、特异度和准确率分别为1.00、0.76和0.92,均高于单一CT征象鉴别诊断效能,3种征象联合鉴别诊断的敏感度未变,而特异度、准确率均下降。 结论:高分辨CT能够清晰显示SPN的形态特征,毛刺征联合分叶征能够提高对SPN良恶性鉴别诊断的敏感度、特异度和准确率。
Abstract:
Aim: To discuss highresolution CT features of solitary pulmonary nodule (SPN) in the differential diagnosis of benign and malignant SPN.Methods: Highresolution CT features of 129 cases of pathologically confirmed SPN(88 cases of malignant SPN and 41 cases of benign SPN) were retrospectively analyzed. Frequencies of different signs in benign and malignant SPN were compared.Results: The most frequent four CT signs of malignant SPN were spicule sign, lobulation, and vascular convergence, which were higher than their frequencies in benign SPN(χ2=26.590,33.661,5.125,P<0.05). When combining any two of spicule sign, lobulation, and vascular convergence as indicator to diagnose benign and malignant SPN, the diagnostic sensitivity, specificity, and accuracy of spicule sign plus lobulation as a combined indicator were 1.00, 0.76, and 0.92, respectively, which were higher than those of single CT sign. Combining all these three signs for diagnosis didn′t affect sensitivity, but showed decreased specificity and accuracy. Conclusion: Highresolution CT could clearly show morphological characteristics of SPN. Combined use of spicule sign and lobulation could increase sensitivity, specificity, and accuracy of the differential diagnosis between benign and malignant SPN.

参考文献/References:

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备注/Memo

备注/Memo:
△男,1972年11月生,硕士,副主任医师,研究方向:肿瘤影像诊断与介入治疗,Email:fangshekelh2000@163.com
更新日期/Last Update: 2014-11-26