[1]曹静,吕志排,党秋红,等.宫颈腺癌组织中C-erbB-2与E-cadherin蛋白的表达[J].郑州大学学报(医学版),2015,(04):503-506.
 CAO Jing,LV Zhipai,DANG Qiuhong,et al.Expressions of CerbB2 and Ecadherin in cervical adenocarcinoma tissue[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2015,(04):503-506.
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宫颈腺癌组织中C-erbB-2与E-cadherin蛋白的表达()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2015年04期
页码:
503-506
栏目:
应用研究
出版日期:
2015-07-20

文章信息/Info

Title:
Expressions of CerbB2 and Ecadherin in cervical adenocarcinoma tissue
作者:
曹静1吕志排1党秋红1郝志伟1李道明2#
1)郑州大学第三附属医院病理科 郑州 4500522)郑州大学第一附属医院病理科 郑州 450052
Author(s):
CAO Jing1 LV Zhipai1 DANG Qiuhong1 HAO Zhiwei1 LI Daoming2
1)Department of Pathology, the Third Affiliated Hospital,Zhengzhou University, Zhengzhou 450052 2)Department of Pathology, the First Affiliated Hospital,Zhengzhou University, Zhengzhou 450052
关键词:
CerbB2Ecadherin宫颈腺癌
Keywords:
CerbB2Ecadherincervical adenocarcinoma
分类号:
R737.33
文献标志码:
A
摘要:
目的:探讨宫颈腺癌组织中CerbB2和Ecadherin蛋白的表达与宫颈腺癌患者临床病理特征的关系。方法:应用免疫组化法检测72例宫颈腺癌组织中CerbB2和Ecadherin蛋白的表达情况,分析二者与宫颈腺癌患者临床病理特征的关系。结果:72例宫颈腺癌组织中,CerbB2高表达31例(43.1%),Ecadherin低表达34例(47.2%)。CerbB2高表达和Ecadherin低表达与宫颈腺癌的分化程度、FIGO分期及淋巴结转移有关(P<0.05)。宫颈腺癌组织中CerbB2与Ecadherin的表达呈负关联(rP=0.600,P<0.001)。结论:CerbB2高表达和Ecadherin低表达与宫颈腺癌的发展有关,可作为判断宫颈腺癌生物学行为的重要参考指标。
Abstract:
CerbB2;Ecadherin;cervical adenocarcinoma

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更新日期/Last Update: 1900-01-01