[1]靳雅楠,张 焱#,程敬亮,等.DCE-MRI及DWI在鉴别乳腺良、恶性病变中的价值[J].郑州大学学报(医学版),2016,(04):530-533.
 JIN Ya'nan,ZHANG Yan,CHENG Jingliang,et al.Diagnostic value of dynamic contrast-enhanced MRI and DWI in breast lesions[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2016,(04):530-533.
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DCE-MRI及DWI在鉴别乳腺良、恶性病变中的价值()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2016年04期
页码:
530-533
栏目:
应用研究
出版日期:
2016-07-20

文章信息/Info

Title:
Diagnostic value of dynamic contrast-enhanced MRI and DWI in breast lesions
作者:
靳雅楠张 焱#程敬亮王莹莹
郑州大学第一附属医院磁共振室 郑州 450052
Author(s):
JIN Ya'nanZHANG YanCHENG JingliangWANG Yingying
Department of MRI,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052
关键词:
乳腺肿瘤 动态增强 磁共振成像 扩散加权成像
Keywords:
breast tumor dynamic contrast enhancement magnetic resonance imaging diffusion weighted imaging
分类号:
R445
摘要:
目的:探讨动态增强MRI(DCE-MRI)及扩散加权成像(DWI)在乳腺良、恶性病变鉴别诊断中的价值。方法:对85例乳腺病变患者行乳腺MRI动态增强及DWI扫描,经后处理获得:时间-信号强度(TIC)曲线类型、达峰时间(Tmax)、早期强化率(EER)、峰值强化率(PER)、信号增强比(SER)、峰值(SImax)及表观扩散系数(ADC)。结果:良性病变62个,恶性病变34个,良性病变的Tmax、PER、SImax、ADC值显著高于恶性病变(P<0.05),良性病变的SER显著低于恶性病变(P<0.05),良、恶性病变EER差异无统计学意义(P=0.869); 良性病变以Ⅰ型曲线为主(45/62),恶性病变以Ⅱ型和Ⅲ型曲线为主(27/34),TIC曲线类型在良、恶性病变中差异有统计学意义(P<0.05); ADC鉴别乳腺良、恶性病变的诊断效能最高(AUC=0.898)。结论:DCE-MRI及DWI对鉴别乳腺病变的良、恶性病变有重要价值。
Abstract:
Aim: To investigate the differential diagnostic value of dynamic contrast-enhanced MRI(DCE-MRI)and diffusion weighed imaging(DWI)in benign and malignant breast lesions.Methods:A total of 85 patients with breast tumors underwent DCE-MRI and DWI,the value of ADC and semi-quantitative parameters including TIC type,Tmax,EER,PER,SER,SImax were measured at a workstation.Differences in these parameters between the benign and malignant groups were compared.Results: There were 62 benign and 34 malignant tumors.The Tmax,PER,SImax,and ADC values of benign tumors were significantly higher than malignant tumors(P<0.05),while the SER value of benign tumors were significantly lower than malignant tumors(P<0.05).There was no statistical difference in EER between benign tumors and malignant tumors(P=0.869).The TIC curves of benign tumors were mostly type Ⅰ(41/62),and the TIC curves of malignant tumors were mostly typeⅡand typeⅢ(27/34).The ADC value had the highest diagnostic efficiency(AUC=0.898).Conclusion: DCE-MRI combined with DWI are of significant value in the differential diagnosis of breast lesions.

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备注/Memo

备注/Memo:
#通信作者,男,1964年6月生,硕士,教授,研究方向:磁共振诊断,E-mail:zhangyanhy@163.com
更新日期/Last Update: 2016-07-20