[1]王帅羊),刘 琳),崔存英),等.肺动脉闭锁姑息手术后住院并发症发生的危险因素分析[J].郑州大学学报(医学版),2017,(03):363-365.[doi:10.13705/j.issn.1671-6825.2017.03.030]
 WAN Shuang),FENG Tianping),WANG Bingyuan),et al.Prevalence and relationship between hypertriglyceridemia-waist and type 2 diabetes mellitus among middle-aged and elderly residents in rural area[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2017,(03):363-365.[doi:10.13705/j.issn.1671-6825.2017.03.030]
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肺动脉闭锁姑息手术后住院并发症发生的危险因素分析()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2017年03期
页码:
363-365
栏目:
应用研究
出版日期:
2017-05-15

文章信息/Info

Title:
Prevalence and relationship between hypertriglyceridemia-waist and type 2 diabetes mellitus among middle-aged and elderly residents in rural area
作者:
王帅羊1)刘 琳2)崔存英2)陈凯玲1)丁全全1)王成增1)#
1)郑州大学附属肿瘤医院,河南省肿瘤医院超声科 郑州 450008 2)河南省心血管病医院超声室 郑州 450003
Author(s):
WAN Shuang1) FENG Tianping2) WANG Bingyuan3) REN Yongcheng3) WANG Fenli4) WANG Shu5) LUO Xinping5) ZHANG Ming5) HU Dongsheng5) YIN Lei2)
1)Health Management Service Guidance Center,the National Health and Family Planning Commission, Beijing 100044 2)Military Region Hospital in Henan, Zhengzhou 450003 3)Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001 4)Institute of Information and Navigation, Air Force Engineering University, Xi'an 710077 5)Medical College, Shenzhen University, Shenzhen, Guangdong 518060
关键词:
高甘油三酯腰围 2型糖尿病 中老年人群 农村
Keywords:
hypertriglyceridemia-waist type 2 diabetes mellitus middle-aged and elderly resident rural area
分类号:
R181.2
DOI:
10.13705/j.issn.1671-6825.2017.03.030
摘要:
目的:分析农村中老年人群高甘油三酯腰围(HTGW)、2型糖尿病(T2DM)的流行现状及两者间的关联。方法:采用整群抽样的方法于2013年和2014年的7~8月对河南某农村地区45~75岁的中老年人群进行横断面调查,收集其人口统计学特征、行为危险因素、人体测量指标和空腹血标本,并进行血糖和脂质谱的检测。结果:共纳入10 218名研究对象,其中男性3 836人(37.54%),中位年龄56.62岁。HTGW共2 845人(27.84%),男性646人(16.84%),女性2 199人(34.46%)。T2DM共1 406人(13.76%),男性469人(12.23%),女性937人(14.68%)。在调整了年龄、血压、吸烟、饮酒、家族史、体力活动、体重指数(BMI)、高密度脂蛋白后,logistic回归分析结果显示与腰围和甘油三酯水平均正常的人群相比,HTGW可增加T2DM的发病风险,其OR(95%CI)为3.810(3.050~4.760)。以性别和BMI为分层变量分析发现,HTGW与T2DM的关联女性高于男性、18.5≤BMI<24.0 kg/m2人群高于24.0≤BMI<28.0 kg/m2人群。结论:该农村地区中老年人群HTGW和T2DM的患病率较高,HTGW是T2DM稳定的危险因素。
Abstract:
Aim: To assess the prevalence and relationship between hypertriglyceridemia-waist(HTGW)and type 2 diabetes mellitus(T2DM)among middle-aged and elderly residents in the rural area of Henan Province.Methods: A population-based cross-sectional study was conducted in middle-aged and elderly residents aged 45 to 75 years in a rural area of Henan Province from July to August of 2013 and 2014. Demographic characteristics, behavioral risk factors and biochemical indexes were collected in this study.Results: Among the 10 218 subjects, 3 836(37.54%)were males, and the median age was 56.62 years. There were 2 845 cases(27.84%)of HTGW(male 16.84%, female 34.46%)and 1 406 cases(13.76%)of T2DM(male 12.23%, female 14.68%). After adjusting age,blood pressure,smoking,drinking alcohol,family history,manual labor,BMI and high density lipoprotein,the results of logistic regression analysis showed that, HTGW was the risk factor of T2DM [OR(95%CI)=3.810(3.050-4.760)]. Stratification analysis according to gender and BMI showed that the association was stronger in females than in males, in 18.5≤BMI<24.0 kg/m2 residents than in 24.0≤BMI<28.0 kg/m2 residents.Conclusion: Among the rural middle-aged and elderly residents, the prevalences of HTGW and T2DM are relatively high, and HTGW is stably and significantly associated with risk of T2DM.

参考文献/References:

[1] BRUNTON S,DAVIDSON JA.Exenatide once weekly:a review of pharmacology and treatment considerations in type 2 diabetes[J].Clin Ther,2016,38(3):582
[2] FEDERATION ID.IDF diabetes atlas[EB/OL].http://www.diabetesatlas.org.
[3] BAILEY DP,SAVORY LA,DENTON SJ,et al.The hypertriglyceridemic waist, waist-to-height ratio, and cardiometabolic risk[J].J Pediatr,2013,162(4):746
[4] REN YC,LUO XP,WANG CJ,et al.Prevalence of hypertriglyceridemic waist and association with risk of type 2 diabetes mellitus: a meta-analysis[J].Diabetes Metab Res Rev,2016,32(4):405
[5] GOMEZ-HUELGAS R,BERNAL-LPEZ MR,VILLALOBOS A,et al.Hypertriglyceridemic waist: an alternative to the metabolic syndrome? Results of the IMAP Study(multidisciplinary intervention in primary care)[J].Int J Obes(Lond),2011,35(2):292
[6] American Diabetes Association.Standards of medical care in diabetes[J].Diabetes Care,2005,28(Suppl 1):S4
[7] FEDERATION ID. The IDF consensus worldwide definition of the metabolic syndrome[EB/OL].http://www.idf.org/metabolic-syndrome.
[8] 中国肥胖问题工作组数据汇总分析协作组.我国成人体重指数和腰围对相关疾病危险因素异常的预测价值:适宜体重指数和腰围切点的研究[J].中华流行病学杂志,2002,23(1):5
[9] 罗小萌,任永成,胡东生.河南省某农村地区中老年女性人群高甘油三酯腰围患病率及其危险因素[J].郑州大学学报(医学版),2015,50(2):221
[10]LEMIEUX I,PASCOT A,COUILLARD C,et al.Hypertriglyceridemic waist:a marker of the atherogenic metabolic triad(hyperinsulinemia; hyperapolipoprotein B; small, dense LDL)in men?[J].Circulation,2000,102(2):179
[11]KAHN HS,VALDEZ R.Metabolic risks identified by the combination of enlarged waist and elevated triacylglycerol concentration[J].Am J Clin Nutr,2003,78(5):928
[12]CARLSSON AC,RISERUS U,ARNLOV J.Hypertriglyceridemic waist phenotype is associated with decreased insulin sensitivity and incident diabetes in elderly men[J].Obesity(Silver Spring),2014,22(2):526
[13]CHEN K,LI P,LI YJ,et al.Sex disparity in the association between hypertriglyceridemic waist phenotype and arterial stiffness in Chinese healthy subjects[J].Postgrad Med,2016,128(8):783
[14]CHEN S,GUO X,YU S,et al.Association between the hypertriglyceridemic waist phenotype, prediabetes, and diabetes mellitus in rural Chinese population:a cross-sectional study[J].Int J Environ Res Public Health,2016,13(4):368

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备注/Memo

备注/Memo:
#通信作者,男,1964年10月生,博士,教授,研究方向:超声诊断,E-mail:czwang1022@163.com
更新日期/Last Update: 2017-05-20