[1]刘艳丽),李君芳),张玉超),等.冻融胚胎移植周期临床结局的影响因素*[J].郑州大学学报(医学版),2017,(04):434-438.[doi:10.13705/j.issn.1671-6825.2017.04.015]
 LIU Yanli),LI Junfang),ZHANG Yuchao),et al.Influence factors of clinical outcomes of frozen-thawed embryo transfer[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2017,(04):434-438.[doi:10.13705/j.issn.1671-6825.2017.04.015]
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冻融胚胎移植周期临床结局的影响因素*()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2017年04期
页码:
434-438
栏目:
应用研究
出版日期:
2017-07-15

文章信息/Info

Title:
Influence factors of clinical outcomes of frozen-thawed embryo transfer
作者:
刘艳丽1)李君芳2)张玉超1)申春艳1)杨 悦1)王兴玲1)#
1)郑州大学第三附属医院生殖中心 郑州 450052;
2)郑州大学第三附属医院检验科 郑州 450052
Author(s):
LIU Yanli1)LI Junfang2)ZHANG Yuchao1)SHEN Chunyan1)YANG Yue1)WANG Xingling1)
1)Reproductive Medicine Center,the Third Affiliated Hospital,Zhengzhou University,Zhengzhou 450052;
2)Department of Clinical Laboratory,the Third Affiliated Hospital,Zhengzhou University,Zhengzhou 450052
关键词:
玻璃化冷冻 冻融胚胎移植 妊娠率 着床率 影响因素
Keywords:
vitrification freezing frozen thawed embryo transfer clinical pregnancy rate implantation rate influence factor
分类号:
R711.6
DOI:
10.13705/j.issn.1671-6825.2017.04.015
摘要:
目的:探讨玻璃化冷冻胚胎复苏移植临床结局的影响因素。方法:回顾性分析2 430个冻融胚胎移植周期,研究患者年龄、授精方式、内膜厚度、胚胎冷冻保存时间、胚胎在平衡液中的平衡时间和胚胎质量对冻融周期胚胎移植结局的影响。结果与结论:年龄(β=-1.029,P<0.001)、胚胎冷冻保存时间(β=-0.101,P<0.05)和胚胎质量(D3胚胎和D5/D6囊胚质量的β分别为-2.824和-2.878,P<0.001)是冻融胚胎移植临床妊娠率的主要影响因素。
Abstract:
Aim: To explore the influence factors of the frozen thawed embryo transfer(FET)outcomes of human vitrified embryos.Methods: A total of 2 430 FET cycles were collected, and the effects of the age of the patients,insemination ways,endometrium thickness,embryo cryopreservation time, the balance time of embryos in equilibrium liquid and the quality of embryo on the clinical outcomes were analyzed.Results and conclusion: The results showed that age(β=-0.101,P<0.001),embryo cryopreservation time(β=-0.101,P<0.05)and embryo quality(D3 β=-2.824,D5YD6 β=-2.878,P<0.001)were the influence factors of clinical pregnancy rate.

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备注/Memo

备注/Memo:
*河南省医学科技攻关项目 201602126; 郑州大学横向科研项目 20160170A
#通信作者,女,1962年2月生,博士,主任医师,教授,研究方向:生殖内分泌与辅助生殖,E-mail:wangxl208@126.com
更新日期/Last Update: 2017-07-20