[1]尤 超),高永举),崔 静).留存肾功能正常者99mTc-DTPA显像参数正常值的建立[J].郑州大学学报(医学版),2018,(01):68-71.[doi:10.13705/j.issn.1671-6825.2017.04.121]
 YOU Chao),GAO Yongju),CUI Jing).Normal reference of 99mTc-DTPA renal dynamic imaging parameters of compensatory residual kidney[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2018,(01):68-71.[doi:10.13705/j.issn.1671-6825.2017.04.121]
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留存肾功能正常者99mTc-DTPA显像参数正常值的建立()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2018年01期
页码:
68-71
栏目:
应用研究
出版日期:
2018-01-20

文章信息/Info

Title:
Normal reference of 99mTc-DTPA renal dynamic imaging parameters of compensatory residual kidney
作者:
尤 超1)高永举2) 崔 静2)
1)河南省省直第一医院内科 郑州 450003 2)河南省人民医院(郑州大学人民医院)核医学科 郑州 450003
Author(s):
YOU Chao1)GAO Yongju2)CUI Jing2)
1)Department of Internal Medicine, the First Provincial Hospital of Henan Province, Zhengzhou 450003 2)Department of Nuclear Medicine, Henan Provincial People's Hospital(People's Hospital of Zhengzhou University), Zhengzhou 450003
关键词:
留存肾 99mTc-DTPA 肾小球滤过率 高峰时间 半排时间
Keywords:
solitary kidney 99mTc-DTPA glomerular filtration rate peak time of nephrogram half time of kidney washout
分类号:
R445.5
DOI:
10.13705/j.issn.1671-6825.2017.04.121
摘要:
目的:建立一侧肾无功能或缺失、对侧肾功能代偿患者99mTc-DTPA肾动态显像肾小球滤过率(GFR)、高峰时间(tb)及半排时间(C1/2)正常参考值范围。方法:回顾分析115例单侧肾功能正常而对侧肾缺如或无功能检查者的99mTc-DTPA肾动态显像结果,统计其GFR、显像剂摄取tb及C1/2。同时收集102例健康供肾者作为正常对照。结果:115例留存肾99mTc-DTPA肾动态显像的GFR、tb、C1/2正常参考值范围分别为(37.19~102.58)mL/min、(2.10~4.23)min、(6.50~21.51)min。无论留存肾是左肾还是右肾,两者的GFR、tb及C1/2比较差异均无统计学意义(P>0.05)。留存肾GFR较供体肾代偿性增加(t=9.363,P<0.001)。留存肾tb较供体肾延长(Z=3.595,P<0.001)。青年组、中年组和老年组组间GFR比较差异有统计学意义(F=6.130,P=0.003),青年组和中年组留存肾较供体肾GFR分别增加了47%和37%。结论:建立留存肾功能正常检查者99mTc-DTPA显像 GFR、tb、C1/2等参数的正常值参考范围,能够客观、有效地评价肾小球滤过功能,为临床诊疗提供依据。
Abstract:
Aim: To establish the normal reference range of compensatory residual kidney function parameters using 99mTc-DTPA renal dynamic imaging.Methods: A total of 115 patients with normal unilateral renal function and the contralateral kidney non-function or received nephrectomy, and 102 donors(control group)were collected. Parameters including glomerular filtration rate(GFR), the peak time of nephrogram(tb)and half time of kidney washout(C1/2)were collected.Results: The normal reference range of GFR,tb, and C1/2 in 115 cases of renal 99mTc-DTPA renal dynamic imaging were(37.19-102.58)mL/min,(2.10-4.23)min,(6.50-21.51)min, respectively. There was no significant difference in GFR,tb, and C1/2 between the residual left and the residual right kidneys(P>0.05). GFR of the residual kidneys was statistically higher than that of donor kidneys(t=9.363,P<0.001). The tb of the residual kidneys was statistically longer than that of normal donor kidneys(Z=3.595,P<0.001). Compared with control group, GFR of the young group and the middle-aged group increased by 47% and 37%(F=6.130,P=0.003), respectively.Conclusion: The established normal reference range of GFR, tb, C1/2 based on 99mTc-DTPA imaging could be impersonality and efficiency to evaluate glomerular filtration function,and provide a basis for clinical diagnosis and treatment.

参考文献/References:

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备注/Memo

备注/Memo:
【基金项目】国家临床重点专科建设项目(国卫办医函〔2013〕544号)
【作者简介】崔静,通信作者,女,1985年4月生,博士,主治医师,研究方向:影像核医学与放射性核素治疗,E-mail:cuijj.zzu@163.com
更新日期/Last Update: 2018-01-20