[1]卓 琳),王国威),叶静陶),等.基于标准赌博法探索EQ-5D量表综合指数模型[J].郑州大学学报(医学版),2018,(01):88-93.[doi:10.13705/j.issn.1671-6825.2017.05.133]
 ZHUO Lin),WANG Guowei),YE Jingtao),et al.Exploring EQ-5D value set with standard gamble method[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2018,(01):88-93.[doi:10.13705/j.issn.1671-6825.2017.05.133]
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基于标准赌博法探索EQ-5D量表综合指数模型()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2018年01期
页码:
88-93
栏目:
应用研究
出版日期:
2018-01-20

文章信息/Info

Title:
Exploring EQ-5D value set with standard gamble method
作者:
卓 琳1)王国威2)叶静陶2)贡佳慧2)刘 毅2)徐 玲3)汪秀英4)
1)新乡医学院基础医学院 河南新乡 453003 2)徐州医科大学公共卫生学院 江苏徐州 221004 3)中国卫生与计划生育委员会统计信息中心 北京 100044 4)徐州市中心医院肾内科 江苏徐州 221009
Author(s):
ZHUO Lin1) WANG Guowei2) YE Jingtao2) GONG Jiahui2) LIU Yi2) XU Ling3) WANG Xiuying4)
1)School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan 4530032)School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 2210043)Center for Statistics and Information, National Health and Family Planning Commission, Bei
关键词:
正交设计 标准赌博法 EQ-5D量表 评分体系
Keywords:
orthogonal design standard gamble method EQ-5D questionnaire value set
分类号:
R195.1
DOI:
10.13705/j.issn.1671-6825.2017.05.133
摘要:
目的:采用正交设计典型状态基于标准赌博法(SG)探索构建欧洲生命质量量表(EQ-5D)评分体系。方法:采用分层整群随机抽样的方法,从医学院校按年级、专业分层抽取在校大学生250人,选取L18(2*3^7)正交设计表得到18个标准状态。应用STATA/SE 12.0构建9个加权最小二乘多元线性回归模型,模型包括11个哑变量。结果:总体水平上以中位数为基础构建的WLS回归模型(模型AMWls00)最优,该模型无常数项、无交互作用N3变量,具有简洁、高效的特点,其调整后决定系数为0.998 8,平均绝对误差为0.031 5,18状态的预测值与均值相关系数为0.976 0,逻辑错误数为0。且生命质量评分曲线具有明显的中国人文化特征。结论:总体水平上以中位数为基础无N3、无常数项的WLS回归模型(AMWls00)是最优模型,该建模方法最为合理。
Abstract:
Aim: To find the EQ-5D value set with the typical state of orthogonal design by the standard gamble(SG)for the general Chinese population.Methods: Using a stratified cluster random sampling method, 250 college students were selected from the medical college stratified by the grade and the major.Eighteen states were designed by L18(2*3^7). WLS multivariate linear regression models were constructed by STATA/SE 12.0. In total, 11 dummy variables were included in these models.Results: AMWls00 was estimated using WLS regression based on median at the aggregate level, and it was the best-performing model. It had no constant or N3 term of interactive variable with the advantages of parsimony and high efficiency(adjusted R2=0.998 8, MAE=0.031 5, r=0.976 0, logical error=0). The quality of life score curve had traditional Chinese cultural characteristics.Conclusion: The WLS regression model based on median at the aggregate level without N3 and constant(AMWls00)yields the best-performing model,and is the most reasonable method to SG modeling valuation.

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备注/Memo

备注/Memo:
【基金项目】国家自然科学基金资助项目(71373183)
【作者简介】汪秀英,通信作者,女,1970年9月生,硕士,主任医师,研究方向:慢性肾脏病患者生命质量评估,E-mail:xzsywxy@163.com
更新日期/Last Update: 2018-01-20