[1]平杰丹),赵俊伟),孙晓旭),等.荨麻疹患者1 355例血清特异性IgE检测及过敏原分析[J].郑州大学学报(医学版),2018,(06):788-791.[doi:10.13705/j.issn.1671-6825.2018.05.018]
 PING Jiedan),ZHAO Junwei),SUN Xiaoxu),et al.Analysis of serum allergen-specific IgE in 1 355 patients with urticaria[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2018,(06):788-791.[doi:10.13705/j.issn.1671-6825.2018.05.018]
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荨麻疹患者1 355例血清特异性IgE检测及过敏原分析()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2018年06期
页码:
788-791
栏目:
应用研究
出版日期:
2018-11-20

文章信息/Info

Title:
Analysis of serum allergen-specific IgE in 1 355 patients with urticaria
作者:
平杰丹12) 赵俊伟12)孙晓旭1)吴 凡12)王央霞12)马小涵12)明 亮12)
1)郑州大学第一附属医院检验科 郑州 450052;2)河南省检验医学重点实验室 郑州 450052
Author(s):
PING Jiedan12) ZHAO Junwei12) SUN Xiaoxu1) WU Fan12) WANG Yangxia12) MA Xiaohan12) MING Liang12)
1)Department of Clinical Laboratory,the First Affiliated Hospital,Zhengzhou University, Zhengzhou 450052;2)Key Clinical Laboratory of Henan Province,Zhengzhou 450052
关键词:
荨麻疹 过敏原 特异性IgE
Keywords:
urticaria allergen specific IgE
分类号:
R593.1
DOI:
10.13705/j.issn.1671-6825.2018.05.018
摘要:
目的:通过特异性IgE(sIgE)检测分析荨麻疹患者过敏原的分布特点。方法:采用ELISA法对1 355例荨麻疹患者进行血清过敏原sIgE检测。结果:1 355例荨麻疹患者过敏原sIgE阳性检出率为69.0%(935例),sIgE阳性检出率较高的吸入性过敏原主要为霉菌(21.5%)、螨(17.4%)和梧桐花粉(14.2%),食物性过敏原主要为鸡蛋(23.5%)和花生(13.1%)。男性患者总IgE增高者检出率高于女性(P<0.001)。13~18岁年龄段人群sIgE检出率达到峰值。结论:荨麻疹患者过敏原以霉菌、鸡蛋、尘螨为主,过敏情况存在性别、年龄差异。
Abstract:
Aim:To explore the prevalence of serum allergen-specific IgE in patients with urticaria.Methods:The serum allergen-specific IgE of 1 355 patients with urticaria was detected by ELISA.Results:The positive rate of allergen-specific IgE in 1 355 patients was 69.0%; the most common inhale allergens were mold(21.5%), mites(17.4%)and phoenix tree pollen(14.2%); while the corresponding ingested allergens were eggs(23.5%)and peanuts(13.1%). The positive rate of total IgE in male patients was higher than that in females(P<0.001). The positive rate of total IgE got to the peak stage in the patients aged 13-18 years.Conclusion:The main allergens of urticaria patients are mold, eggs and mites, and the status of the patients varied by sex and age.

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备注/Memo

备注/Memo:
【基金项目】国家自然科学基金资助项目(81501715)
【作者简介】明亮,男,通信作者,1964年1月生,博士,主任技师,研究方向:临床检验,E-mail:mingliang3072@163.com
更新日期/Last Update: 2018-11-20