[1]刘继亭),郭永豪),徐 瑾),等.河南省人群HBsAb及5岁以下儿童HBsAg阳性率调查[J].郑州大学学报(医学版),2019,(01):81-84.[doi:10.13705/j.issn.1671-6825.2018.05.091]
 LIU Jiting),GUO Yonghao),XU Jin),et al.Investigation on HBsAb positive rate in Henan population and HBsAg positive rate in children under 5 years old[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2019,(01):81-84.[doi:10.13705/j.issn.1671-6825.2018.05.091]
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河南省人群HBsAb及5岁以下儿童HBsAg阳性率调查()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2019年01期
页码:
81-84
栏目:
应用研究
出版日期:
2019-01-20

文章信息/Info

Title:
Investigation on HBsAb positive rate in Henan population and HBsAg positive rate in children under 5 years old
作者:
刘继亭1)郭永豪2)徐 瑾2)郭万申1)
1)郑州大学公共卫生学院流行病学教研室 郑州 450001 2)河南省疾病预防控制中心免疫规划所 郑州 450016
Author(s):
LIU Jiting1)GUO Yonghao2)XU Jin2)GUO Wanshen1)
1)Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001 2)Institute for Immunization Planning,Henan Provincial Center for Disease Control and Prevention,Zhengzhou 450016
关键词:
河南省 乙肝
Keywords:
Henan Province hepatitis B
分类号:
R186
DOI:
10.13705/j.issn.1671-6825.2018.05.091
摘要:
目的:了解河南省人群乙肝表面抗体(HBsAb)阳性率和5岁以下儿童乙肝表面抗原(HBsAg)阳性率,为河南省制定乙肝免疫规划策略提供科学依据。方法:采用多阶段随机抽样的方法从河南省抽取调查对象845人,分为7个年龄组。调查对象填写调查问卷,按标准采集血样,用ELISA法检测HBsAb,并对5岁以下儿童进行HBsAg和乙肝核心抗体(HBcAb)检测。结果:调查对象HBsAb阳性率为82.13%; 随着年龄的增长,HBsAb阳性率下降; <1岁组人群HBsAb水平最高(99.16%),≥20岁组最低(67.96%); 不同年龄、性别、地区、职业的人群间HBsAb阳性率差异均有统计学意义(P<0.05)。5岁以下儿童HBsAb阳性率为87.72%,HBsAg和HBcAb阳性率均为0.22%。结论:河南省人群HBsAb水平较高; 5岁以下儿童HBsAg阳性率低,完成了世界卫生组织对西亚太地区提出的降至1%以下的目标。
Abstract:
Aim:To understand the positive rate of HBsAb in Henan population and HBsAg positive rate in children under the age of 5 years, so as to provide scientific basis for formulating strategies for hepatitis B immunization in Henan Province.Methods:A total of 845 individuals including 7 age groups were selected using multi-stage random sampling, and the questionnaire survey was performed. HBsAb was detected using ELISA in the whole population. HBsAg and HBcAb were additionally determined in children under the age of 5 years.Results:The positive rate of HBsAb was 82.13% in 845 individuals, which decreased with age; the positive rate of HBsAb was the highest in <1 year group(99.16%), and the lowest in the group aged 20 years or above(67.96%); the positive rate of HBsAb was different in people with different age, gender, region, or occupations(P<0.05). The positive rate of HBsAb was 87.72%,and that of HBsAg and HBcAb was both 0.22% in the children under 5 years old.Conclusion:The HBsAb level of population in Henan Province is relatively high, and the HBsAg positive rate is low in the children under 5 years old, which has completed the target(1% below)proposed by WHO for the West Asia Pacific region.

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备注/Memo

备注/Memo:
【基金项目】河南省科技攻关项目(182102311139); 中国肝炎基金会乙肝防控科研基金项目(YGFK20170023) 【作者简介】郭万申,通信作者,1966年4月生,本科,教授,研究方向:流行病与卫生统计学, E-mail:cdcgws@163.com
更新日期/Last Update: 2019-01-20