[1]刘 英),李志业),张 强),等.血压变异性与原发性高血压患者心房颤动的关系[J].郑州大学学报(医学版),2019,(01):126-130.[doi:10.13705/j.issn.1671-6825.2018.05.097]
 LIU Ying),LI Zhiye),ZHANG Qiang),et al.Correlation between blood pressure variability and atrial fibrillation[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2019,(01):126-130.[doi:10.13705/j.issn.1671-6825.2018.05.097]
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血压变异性与原发性高血压患者心房颤动的关系()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2019年01期
页码:
126-130
栏目:
应用研究
出版日期:
2019-01-20

文章信息/Info

Title:
Correlation between blood pressure variability and atrial fibrillation
作者:
刘 英1)李志业2)张 强1)周雨菡1)孙彩红1)方士杰1)徐晓婷1)
1)郑州大学第二附属医院心血管内科 郑州 450014 2)郑州大学第二附属医院医政科 郑州 450014
Author(s):
LIU Ying1)LI Zhiye2)ZHANG Qiang1)ZHOU Yuhan1)SUN Caihong1)FANG Shijie1)XU Xiaoting1)
1)Department of Cardiology, the Second Affiliated Hospital, Zhengzhou University, Zhengzhou 450014 2)Department of Medical Affairs,the Second Affiliated Hospital,Zhengzhou University,Zhengzhou 450014
关键词:
高血压 心房颤动 超声心动图 血压监测 危险因素
Keywords:
hypertension atrial fibrillation echocardiography blood pressure monitoring risk factor
分类号:
R541
DOI:
10.13705/j.issn.1671-6825.2018.05.097
摘要:
目的:探讨血压变异性与原发性高血压患者心房颤动(房颤)的关系。方法:高血压患者233例,其中房颤组81例,非房颤组152例,采集临床基线资料、动态血压、超声心动图等参数; 应用logistic回归及受试者工作特征(ROC)曲线分析血压变异性对房颤的影响。结果:房颤组24 h加权收缩压标准差、24 h加权舒张压标准差和脉压明显高于非房颤组(P<0.05)。Logistic回归分析显示年龄、尿酸、体重指数、24 h加权收缩压标准差、24 h加权舒张压标准差、脉压、左房内径、左室质量指数是房颤的独立危险因素; ROC曲线显示24 h加权收缩压标准差、24 h加权舒张压标准差[曲线下面积(95%CI)分别为0.690(0.619~0.761)和0.708(0.642~0.774)]对于房颤发生的预测比脉压[曲线下面积(95%CI)为0.650(0.576~0.725)]更有价值。结论:24 h加权收缩压标准差、24 h加权舒张压标准差和脉压是房颤的独立危险因素; 24 h加权收缩压和舒张压标准差对于房颤发生的预测更具有价值。
Abstract:
Aim:To investigate the correlation between blood pressure variability and atrial fibrillation(AF)in patients with essential hypertension.Methods: A retrospective study of 233 patients with essential hypertension, including 81 patients in the AF group and 152 in the AF-free group was performed.The patients accepted ambulatory blood pressure monitoring and echocardiography examination,and their baseline data were recorded. The effect of blood pressure variability on AF was analyzed using logistic regression and receiver operating characteristic(ROC)curves.Results: It was shown that 24 h weighted standard deviation of systolic blood pressure, 24 h weighted standard deviation of diastolic blood pressure, and in the AF group pulse pressure were significantly higher than those in the AF-free group(P<0.05). Logistic regression analysis showed age, uric acid, body mass index, and 24 h weighted standard deviation of systolic blood pressure, 24 h weighted standard deviation of diastolic pressure, pulse pressure, left atrium diameter, and left ventricular mass index were independent risk factors for AF; ROC curves showed area under the curve(95%CI)of 24 h weighted standard deviation of systolic blood pressure and 24 h weighted standard deviation of diastolic pressure was 0.690(0.619-0.761), 0.708(0.642-0.774)which was more valuable for the diagnosis of AF than pulse pressure [area under the curve(95%CI)of 0.650(0.576-0.725)].Conclusion: 24 h weighted standard deviation of systolic blood pressure, 24 h weighted standard deviation of diastolic blood pressure, and pulse pressure are independent risk factors for AF; 24 h weighted standard deviation of diastolic blood pressure and systolic blood pressure have greater diagnostic value for AF than pulse pressure.

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备注/Memo

备注/Memo:
【基金项目】河南省科技攻关项目(182102310509) 【作者简介】李志业,通信作者,男,1972年6月生,硕士,主任药师,研究方向:西药制剂,E-mail:xclzy@126.com
更新日期/Last Update: 2019-01-20