[1]王国威),刘丁阳),马艺菲),等.徐州市肾功能下降患病率的年龄-时期-队列模型分析[J].郑州大学学报(医学版),2019,(02):241-244.[doi:10.13705/j.issn.1671-6825.2018.09.038]
 WANG Guowei),LIU Dingyang),MA Yifei),et al.Analysis of decreased renal function morbidity in Xuzhou City based on age-period-cohort model[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2019,(02):241-244.[doi:10.13705/j.issn.1671-6825.2018.09.038]
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徐州市肾功能下降患病率的年龄-时期-队列模型分析()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2019年02期
页码:
241-244
栏目:
应用研究
出版日期:
2019-03-20

文章信息/Info

Title:
Analysis of decreased renal function morbidity in Xuzhou City based on age-period-cohort model
作者:
王国威1)刘丁阳1)马艺菲1)贡佳慧1)卓 琳2)徐 玲3)汪秀英4)卓 朗1)
1)徐州医科大学公共卫生学院 江苏徐州 221004 2)新乡医学院基础医学院 河南新乡 453000 3)国家卫生健康委员会统计信息中心 北京 100044 4)徐州市中心医院肾内科 江苏徐州 221004
Author(s):
WANG Guowei1)LIU Dingyang1)MA Yifei1)GONG Jiahui1)ZHUO Lin2)XU Ling3)WANG Xiuying4)ZHUO Lang1)
1)School of Public Health,Xuzhou Medical University,Xuzhou,Jiangsu 221004 2)School of Basic Medicine,Xinxiang Medical College,Xinxiang,Henan 453000 3)Center for Statistics and Information,National Health and Family Planning Commission,Beijing 100044 4)Department of Nephrology,Xuzhou Central Hospital,Xuzhou,Jiangsu 221004
关键词:
年龄-时期-队列模型 肾功能下降 混合效应
Keywords:
age-period-cohort model decreased renal function mixed effects
分类号:
R18
DOI:
10.13705/j.issn.1671-6825.2018.09.038
摘要:
目的:应用年龄-时期-队列(APC)模型分析肾功能下降患病率,为慢性肾脏病(CKD)病因探索、诊疗和预防策略提供科学依据。方法:利用2005~2012年徐州市中心医院体检数据,采用APC模型和混合效应法估计肾功能下降患病率的年龄、时期和出生队列效应。结果:APC模型结果显示,肾功能下降患病风险随年龄增长而增加; 时期效应呈下降趋势,但效应值波动范围较小; 出生队列效应在1922~1925年至1926~1929年出生队列、1946~1949年至1950~1953年出生队列、1958~1961年至1966~1969年出生队列和1974~1977年至1978~1981年出生队列呈上升趋势。结论:肾功能下降患病风险的变化可能与重大历史事件密切相关; APC混合效应模型能够较好地描述患病率的效应趋势。
Abstract:
Aim:To analyze the trends of decreased renal function morbidity using age-period-cohort(APC)model, and to provide scientific evidence for exploring the cause of the chronic kidney disease, diagnosing and developing preventive strategies.Methods:The data were obtained from the health examination center of Xuzhou Central Hospital from 2005 to 2012. APC model and mixed effects were applied to assess the effects of age, period and cohort on the risk of decreased renal function morbidity.Results:APC model analysis indicated the risk of decreased renal function morbidity increased with age and decreased with period, but the fluctuation range was small. The cohort effect rose during 1922-1925 years and 1926-1929, 1946-1949 to 1950-1953, 1958-1961 to 1966-1969,and 1974-1977 to 1978-1981 years.Conclusion:The fluctuation of the incidence of renal dysfunction may be related to the major historical events and the APC mixed model can describe the three effects of the prevalence rate well.

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备注/Memo

备注/Memo:
【基金项目】国家自然科学基金面上项目(71373183); 江苏省社科研究(青年精品)重点课题(13SQB-058); 徐州市科技项目(XF10C051,XZZD1239)
【作者简介】卓朗,通信作者,男,1972年3月生,博士,教授,研究方向:慢性肾脏病,E-mail:episoft @163.com
更新日期/Last Update: 2019-03-20