[1]张 宇,邢 钰,邢军辉,等.左室心肌自动功能成像技术应变参数对冠状动脉狭窄程度的判定价值[J].郑州大学学报(医学版),2019,(02):249-253.[doi:10.13705/j.issn.1671-6825.2018.08.125]
 ZHANG Yu,XING Yu,XING Junhui,et al.Value of left ventricular myocardial strain parameters by real-time automated function imaging for assessment of coronary arterystenosis degree[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2019,(02):249-253.[doi:10.13705/j.issn.1671-6825.2018.08.125]
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左室心肌自动功能成像技术应变参数对冠状动脉狭窄程度的判定价值()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2019年02期
页码:
249-253
栏目:
应用研究
出版日期:
2019-03-20

文章信息/Info

Title:
Value of left ventricular myocardial strain parameters by real-time automated function imaging for assessment of coronary arterystenosis degree
作者:
张 宇邢 钰邢军辉秦石成李 凌
郑州大学第一附属医院心血管内科 郑州 450052
Author(s):
ZHANG Yu XING YuXING JunhuiQIN Shicheng LI Ling
Department of Cardiology,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052
关键词:
自动功能成像 冠状动脉狭窄 心肌应变 斑点追踪显像
Keywords:
automated function imaging coronary artery stenosis myocardial strain speckle tracking imaging
分类号:
R540.4+5
DOI:
10.13705/j.issn.1671-6825.2018.08.125
摘要:
目的:探讨左室心肌自动功能成像(AFI)技术应变参数判定冠状动脉狭窄程度的价值。方法:选择拟诊冠心病行冠状动脉造影检查者100例。应用AFI获得左心室壁17个节段应变牛眼图,测量各冠状动脉分支对应节段的局部峰值纵向应变(LLPS)和左心室整体峰值纵向应变(GLPS)。结果:各支冠脉的LLPS和GLPS均有随狭窄程度增高而下降的趋势。前降支、回旋支中或重度狭窄组LLPS和GLPS均小于无狭窄或轻度狭窄组(P<0.05); 右冠状动脉重度狭窄组GLPS小于无狭窄组(P<0.05)。ROC曲线分析结果显示,LLPS可判定前降支和回旋支中度以上狭窄,AUC(95%CI)分别为0.719(0.619~0.818)和0.755(0.678~0.873); 对右冠状动脉狭窄的判定无统计学意义; GLPS可用于中度以上冠脉狭窄的判定,AUC(95%CI)为0.823(0.738~0.907),截断值为20.25时,灵敏度和特异度分别为86.5%和74.6%。结论:AFI能够反映患者狭窄冠状动脉对应心肌的应变参数变化,可在一定程度上评估冠状动脉狭窄程度。
Abstract:
Aim:To explore the value of left ventricular myocardial strain parameters by real-time automated function imaging(AFI)for assessment of coronary stenosis degree.Methods:One hundred subjects who underwent coronary angiography were enrolled and were examined by color doppler echocardiography before angiography,and the strain map of 17 segments of the left ventricular wall were obtained by AFI. The local longitudinal peak strain(LLPS)of the coronary artery branches and the overall global longitudinal peak strain(GLPS)were measured.Results:LLPS of every coronary artery branch and GLPS had a tendency to decrease with the degree of stenosis.LLPS and GLPS of patients with non-stenosis or mild stenosis in anterior descending and circumflex branch were higher than those of patients with moderate or severe stenosis(P<0.05). GLPS in patients with severe stenosis of right coronary artery was lower than the patients with non-stenosis(P<0.05).The results of ROC showed that LLPS had high diagnostic efficacy for judging moderate and severe stenosis in anterior descending and circumflex branch, AUC(95%CI)was 0.719(0.619-0.818)and 0.755(0.678-0.873),respectively,but not for the right coronary artery; GLPS had high diagnostic efficacy for the judging moderate and severe stenosis, AUC(95%CI)was 0.823(0.738-0.907), and the sensitivity and specificity were 86.5% and 74.6% when the cutoff value was 20.25.Conclusion:AFI could reflect the changes of strain parameters of the myocardial corresponding stenostic coronary artery, and can assess the degree of coronary artery stenosis to some extent.

参考文献/References:

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备注/Memo

备注/Memo:
【基金项目】河南省高等学校重点科研项目(16A320049); 河南省医学科技攻关计划项目(201403026)
【作者简介】李凌,通信作者,女,1963年3月生,硕士,教授,研究方向:心血管疾病诊治,E-mail:liling63035@sina.com
更新日期/Last Update: 2019-03-20