[1]刘 杨),巴玉峰),刘 如),等.胸段食管鳞癌患者术后预后影响因素[J].郑州大学学报(医学版),2019,(04):496-499.[doi:10.13705/j.issn.1671-6825.2018.12.094]
 LIU Yang),BA Yufeng),LIU Ru),et al.Influencing factors of postoperation prognosis of patients with thoracic esophageal squamous cell carcinoma[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2019,(04):496-499.[doi:10.13705/j.issn.1671-6825.2018.12.094]
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胸段食管鳞癌患者术后预后影响因素()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2019年04期
页码:
496-499
栏目:
食管癌研究
出版日期:
2019-07-20

文章信息/Info

Title:
Influencing factors of postoperation prognosis of patients with thoracic esophageal squamous cell carcinoma
作者:
刘 杨1)巴玉峰2)刘 如1)贺春语1)杨原源1)李浩淼2)姚志华3)王刚成4)李定杰1)蒋 月1)
1)郑州大学附属肿瘤医院(河南省肿瘤医院)放疗科 郑州 450008;2)郑州大学附属肿瘤医院(河南省肿瘤医院)胸外科 郑州 450008;3)郑州大学附属肿瘤医院(河南省肿瘤医院)内科 郑州 450008;4)郑州大学附属肿瘤医院(河南省肿瘤医院)普外科 郑州 450008
Author(s):
LIU Yang1)BA Yufeng2)LIU Ru1)HE Chunyu1) YANG Yuanyuan1) LI Haomiao2)YAO Zhihua3)WANG Gangcheng4)LI Dingjie1)JIANG Yue1)
1)Department of Radiation Oncology,the Affiliated Cancer Hospital of Zhengzhou University(Henan Cancer Hospital), Zhengzhou 450008;2)Department of Thoracic Surgery,the Affiliated Cancer Hospital of Zhengzhou University(Henan Cancer Hospital),Zhengzhou 450008;3)Department of Internal Medicine,the Affiliated Cancer Hospital of Zhengzhou University(Henan Cancer Hospital),Zhengzhou 450008;4)Department of General Surgery,the Affiliated Cancer Hospital of Zhengzhou University(Henan Cancer Hospital),Zhengzhou 450008
关键词:
食管鳞癌 根治切除术 术后预后
Keywords:
esophageal squamous cell carcinoma radical resection postoperation prognosis
分类号:
R735.1
DOI:
10.13705/j.issn.1671-6825.2018.12.094
摘要:
目的:探讨胸段食管鳞癌患者根治切除术后预后的影响因素。方法:收集381例接受根治切除术治疗的胸段食管鳞癌患者的临床、病理与随访资料,采用Kaplan-Meier法进行生存分析,应用Cox回归模型筛选术后预后影响因素。结果:381例患者术后1、2、3 a生存率分别为87.9%、72.2%、68.2%。Cox回归分析结果显示,N分期是胸段食管鳞癌根治切除术后预后的独立危险因素, N1、N2、N3期相较N0期的HR(95%CI)分别为2.528(1.345~4.751)、4.122(1.571~10.815)和8.387(2.356~29.860)。结论:N分期是胸段食管鳞癌根治切除术后预后的独立危险因素。
Abstract:
Aim:To discuss the influencing factors of prognosis of patients with thoracic esophageal squamous cell carcinoma after radical resection.Methods:Clinicopathological and follow-up data of 381 patients with thoracic esophageal squamous cell carcinoma who underwent radical resection were collected. Kaplan-Meier survival analysis was conducted, and the influencing factors of prognosis were analyzed using Cox regression model.Results:The overall 1-, 2-, 3-year survival rates were 87.9%, 72.2%, 68.2%, respectively. Cox analysis showed that N stage was the independent risk factor for the postoperation prognosis(P<0.05),the HR(95%CI)of N1,N2 and N3 stage compared with N0 stage was 2.528(1.345-4.751),4.122(1.571-10.815)and 8.387(2.356-29.860),respectively.Conclusion:N stage is the independent risk factor for the patients with thoracic esophageal squamous cell carcinoma after radical resection.

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备注/Memo

备注/Memo:
【基金项目】 河南省科技厅重点科技攻关项目(142102310502); 河南省卫生厅普通科技攻关项目(201403026); 河南省卫生厅科技攻关指导性计划(201304058)
【作者简介】蒋月,通信作者,女,1965年11月生,本科,主任医师,研究方向:食管癌的放射治疗,E-mail:sunny5799@126.com
更新日期/Last Update: 2019-07-20