[1]吴正阳,毕永华,任建庄,等.可回收支架联合搅拌溶栓、球囊扩张治疗布加综合征合并下腔静脉血栓[J].郑州大学学报(医学版),2019,(05):654-657.[doi:10.13705/j.issn.1671-6825.2019.06.108]
 WU Zhengyang,BI Yonghua,REN Jianzhuang,et al.Efficacy of retrievable stents combined with agitation thrombolysis and balloon angioplasty for treatment of Budd-Chiari syndrome complicated with inferior vena cava thrombosis[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2019,(05):654-657.[doi:10.13705/j.issn.1671-6825.2019.06.108]
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可回收支架联合搅拌溶栓、球囊扩张治疗布加综合征合并下腔静脉血栓()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2019年05期
页码:
654-657
栏目:
系列研究
出版日期:
2019-09-20

文章信息/Info

Title:
Efficacy of retrievable stents combined with agitation thrombolysis and balloon angioplasty for treatment of Budd-Chiari syndrome complicated with inferior vena cava thrombosis
作者:
吴正阳毕永华任建庄丁鹏绪周朋利张文广焦德超韩新巍
郑州大学第一附属医院放射介入科 郑州 450052
Author(s):
WU Zhengyang BI Yonghua REN Jianzhuang DING Pengxu ZHOU Pengli ZHANG Wenguang JIAO Dechao HAN Xinwei
Department of Interventional Radiology,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052
关键词:
布加综合征 可回收支架 下腔静脉血栓形成 球囊扩张成形术 搅拌溶栓
Keywords:
Budd-Chiari syndrome retrievable stent inferior vena cava thrombosis balloon angioplasty agitation thrombolysis
分类号:
R575
DOI:
10.13705/j.issn.1671-6825.2019.06.108
摘要:
目的:分析采用可回收支架联合搅拌溶栓、球囊扩张治疗布加综合征(BCS)合并下腔静脉(IVC)血栓形成的效果。方法:针对40例BCS合并IVC血栓形成的患者,对闭塞的IVC采用球囊预扩张部分恢复IVC管腔,以顺利放置可回收支架,然后进行搅拌溶栓。血栓消失后取出支架,必要时采用大球囊扩张。术后采用彩色多普勒超声检查观察IVC通畅程度。结果:所有患者均成功进行可回收支架置入、搅拌溶栓和球囊扩张,支架置入后IVC均立即恢复通畅。1例支架放置6 h后死于急性肺栓塞,1例出院0.4个月后死于冠心病,1例出院0.8个月后死于肝功能衰竭。37例支架放置8~29 d后取出,取出技术成功率为97.3%(36/37),1例因支架断裂改用外科手术取出。34例成功随访,初次通畅率和二次通畅率分别为94.1%(32/34)和97.1%(33/34),术后5 a和10 a生存率分别为89.5%和67.1%。结论:可回收支架联合搅拌溶栓、球囊扩张治疗BCS合并IVC血栓形成安全、有效,远期疗效良好。
Abstract:
Aim:To analyze the efficacy of retrievable stents combined with agitation thrombolysis and balloon angioplasty for the treatment of Budd-Chiari syndrome(BCS)complicated with thrombosis of inferior vena cava(IVC).Methods:For 40 patients with BCS complicated with IVC thrombosis, balloon pre-dilatation was used to restore IVC lumen in the occluded IVC, so as to place the retrievable stent smoothly, and then stirring thrombolysis was performed. After the thrombus disappeared, the stent was removed and large balloon dilatation was used if necessary. The patency of IVC was observed by color Doppler ultrasonography after operation.Results:All patients were successfully treated with retrievable stent implantation, and agitation thrombolysis and balloon angioplasty. IVC recovered immediately after stent implantation. One died of acute pulmonary embolism 6 hours after stent placement, one died of coronary heart disease 0.4 months after discharge, and one died of liver failure 0.8 months after discharge.A total of 37 stents were removed after 8 to 29 days of stent placement. The successful rate of stent removal was 97.3%(36/37). One stent was removed surgically because of stent rupture. Thirty-four cases were followed up successfully. The first patency rate and the second patency rate were 94.1%(32/34)and 97.1%(33/34), respectively. The 5-year and 10-year survival rates were 89.5% and 67.1%,respectively.Conclusion:The retrievable stents combined with agitation thrombolysis,balloon angioplasty are safe and effective in the treatment of BCS complicated with IVC thrombus, with a satisfactory long-term efficacy.

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备注/Memo

备注/Memo:
【基金项目】国家自然科学基金项目(81501569)
【作者简介】韩新巍,通信作者,男,1958年6月生,博士,主任医师,研究方向:各类疾病的介入治疗,E-mail:hanxinwei2006@163.com
更新日期/Last Update: 2019-09-20