[1]僧明华,赵 升,吕宛玉,等.河南省2015~2018年B型流感流行特征分析[J].郑州大学学报(医学版),2019,(05):712-716.[doi:10.13705/j.issn.1671-6825.2018.09.162]
 SENG Minghua,ZHAO Sheng,LYU Wanyu,et al.Epidemiological characteristics of influenza B in Henan Province, 2015-2018[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2019,(05):712-716.[doi:10.13705/j.issn.1671-6825.2018.09.162]
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河南省2015~2018年B型流感流行特征分析()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2019年05期
页码:
712-716
栏目:
应用研究
出版日期:
2019-09-20

文章信息/Info

Title:
Epidemiological characteristics of influenza B in Henan Province, 2015-2018
作者:
僧明华赵 升吕宛玉杨建辉徐 瑾
河南省疾病预防控制中心 郑州450016
Author(s):
SENG MinghuaZHAO ShengLYU WanyuYANG JianhuiXU Jin
Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450016
关键词:
流感B型 流行特征 防控策略 河南省
Keywords:
influenzasubtype B epidemiological characteristics prevention and control strategy Henan Province
分类号:
R183
DOI:
10.13705/j.issn.1671-6825.2018.09.162
摘要:
目的:分析河南省2015~2018年B型流感的流行特征,为流感防控策略的制定提供依据。方法:对河南省22家流感监测哨点医院的流感样病例(ILI)咽拭子标本进行荧光定量PCR检测,对B型流感病毒阳性标本进行统计分析。结果:河南省2015~2018年共检测48 123例ILI病例标本,其中B型流感病毒核酸检测阳性4 433例。2015~2016年、2017~2018年B型流感病毒占所有流感病毒核酸检测阳性标本的比例分别为67.98%、43.54%,高于2016~2017年(6.75%)(P<0.05)。2015~2016年和2017~2018年B型流感病毒阳性率高于2016~2017年(P<0.05); 每年11月到次年4月为B型流感的流行高峰期; 感染人群以5~15岁托幼儿童和学生为主; 2015~2016年和2017~2018年感染人群中男性感染率高于女性(P<0.05); 各个监测年度河南省各市B型流感病毒核酸阳性率不同; 病毒分离以高滴度一代细胞分离毒株为主。结论:B型流感病毒具有感染率高、毒力强、易培养的特点,是河南省2015~2016年和2017~2018年流感流行的主要型别,儿童和学生是B型流感防控的重点人群。
Abstract:
Aim:To analyze the epidemiological characteristics of influenza B in Henan Province from 2015 to 2018,so as to provide the basis for the formulation of influenza prevention and control strategies.Methods:Influenza like illness(ILI)swabs collected by 22 influenza sentinel hospitals in Henan Province were detected by fluorescence quantitative PCR,and the positive specimens of influenza B virus were analyzed.Results:A total of 48 123 ILI specimens were detected in Henan Province during 2015-2018, and 4 433 were positive of influenza B virus. Influenza B virus positive samples accounted for 67.98% and 43.54% of all the influenza virus nucleic acid positive samples during 2015-2016 and 2017-2018,respectively,higher than that during 2016-2017(6.75%)(P<0.05).The positive rate of influenza B virus in 2015-2016 and 2017-2018 was higher than that in 2016-2017(P<0.05). The epidemic peak period of influenza B was from November to April of next year, and the majority of the infected people were children and students aged 5-15 years. The influenza B infection rate of males was higher than that of females in the infected population during 2015-2016 and 2017-2018(P<0.05). The positive rate of the different cities was variant. The characteristics of virus isolation showed that there were mainly high titer and the first generation cell isolates.Conclusion:Influenza B virus in Henan Province during 2015-2018 had the characteristics of high infection rate, strong virulence,and easy cultivation. It was the main epidemic type during 2015-2016 and 2017-2018 in Henan Province, and children and students were the key population of influenza B prevention and control.

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备注/Memo

备注/Memo:
【基金项目】河南省科技攻关计划项目(172102310093)
【作者简介】徐瑾,通信作者,女,1972年1月生,硕士,副主任医师,研究方向:分子流行病学,E-mail:xujinjc@163.com
更新日期/Last Update: 2019-09-20