[1]张宇恒,丁素英.非酒精性脂肪肝与胆囊结石的关系分析[J].郑州大学学报(医学版),2019,(05):716-719.[doi:10.13705/j.issn.1671-6825.2018.12.121]
 ZHANG Yuheng,DING Suying.Analysis on relationship between non-alcoholic fatty liver disease and gallstone disease[J].JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES),2019,(05):716-719.[doi:10.13705/j.issn.1671-6825.2018.12.121]
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非酒精性脂肪肝与胆囊结石的关系分析()
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《郑州大学学报(医学版)》[ISSN:1671-6825/CN:41-1340/R]

卷:
期数:
2019年05期
页码:
716-719
栏目:
应用研究
出版日期:
2019-09-20

文章信息/Info

Title:
Analysis on relationship between non-alcoholic fatty liver disease and gallstone disease
作者:
张宇恒丁素英
郑州大学第一附属医院体检科 郑州 450052
Author(s):
ZHANG YuhengDING Suying
The Physical Examination Center,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052
关键词:
非酒精性脂肪肝 胆囊结石
Keywords:
non-alcoholic fatty liver disease gallstone disease
分类号:
R575
DOI:
10.13705/j.issn.1671-6825.2018.12.121
摘要:
目的:探讨非酒精性脂肪肝与胆囊结石的关系,并为胆囊结石的防治提供新的思路。方法:选取在郑州大学第一附属医院体检中心进行健康体检的受检者6 592人为研究对象,收集其一般资料以及体格检查、生化指标检测、腹部超声检查的资料。结果:6 592人中,304(4.61%)例患有胆囊结石。单因素分析显示,年龄、血压、BMI、BUN、空腹血糖、TG、TC以及非酒精性脂肪肝与胆囊结石有关(P<0.05); logistic回归分析显示,非酒精性脂肪肝(OR=3.856,95%CI=2.543~5.847)、高龄(OR=2.804,95%CI=1.971~3.988)、高BMI(OR=1.324,95%CI=1.007~1.743)及高SBP(OR=1.437,95%CI=1.085~1.902)是胆囊结石发生的危险因素。结论:非酒精性脂肪肝与胆囊结石的发生有密切关系,同时胆囊结石发生的高危因素还有高龄、高BMI及高SBP,预防非酒精性脂肪肝或可降低胆囊结石的发病率。
Abstract:
Aim:To investigate the relationship between non-alcoholic fatty liver disease(NAFLD)and gallstone disease(GSD).Methods:A total of 6 592 individuals accepted physical examination in the Physical Examination Center of the First Affiliated Hospital of Zhengzhou University were included in this study. Physical examination data including laboratory examination data and hepatic ultrasound examination data were collected.Results:Age,blood pressure,BMI,BUN,fasting plasma glucose, triglyceride,total cholesterol and NAFLD were related to GSD(P<0.05). Based on logistic regression,NAFLD(OR=3.856,95%CI=2.543-5.847),advanced age(OR=2.804,95%CI=1.971-3.988),higher BMI(OR=1.324,95%CI=1.007-1.743)and high systolic pressure(OR=1.437,95%CI=1.085-1.902)were risk factors of GSD.Conclusion:NAFLD is associated with an increased risk of GSD. Advanced age, higher BMI and higher systolic pressure are also related to a higher risk of GSD. Prevention of NAFLD might reduce the incidence of GSD.

参考文献/References:

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备注/Memo

备注/Memo:
【基金项目】河南省科技攻关计划项目(22170050)
【作者简介】丁素英,通信作者,女,1971年5月生,硕士,教授,研究方向:健康管理,E-mail: fccdingsy@zzu.edu.cn
更新日期/Last Update: 2019-09-20